BeOne Medicines Ltd.
Business
BeOne Medicines Ltd. is a global oncology company that discovers, develops and commercializes cancer therapies. It offers targeted small molecules, monoclonal antibodies, antibody‑drug conjugates, multispecific and bispecific antibodies, protein degraders (CDACs), and in‑licensed oncology medicines, with marketed products such as BRUKINSA and TEVIMBRA. Its operations are organized around hematology and solid tumor franchises, research and development (clinical and preclinical pipelines), manufacturing, and commercial partnerships. The company sells and develops products worldwide across the U.S., Europe, China, Japan, Asia Pacific, Latin America and other markets via direct commercial teams, partnerships and global clinical trial networks.
Summary from filing dated 2025-02-27
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Total revenues | 5,343 | 3,810 | 2,459 | 1,416 | 1,176 | |
| Gross profit | 4,674 | 3,216 | 2,079 | 1,129 | 1,011 | |
| Research and development | 2,146 | 1,953 | 1,779 | 1,641 | 1,459 | |
| Selling, general and administrative | 2,081 | 1,831 | 1,508 | 1,279 | 990 | |
| Total operating expenses | 4,227 | 3,784 | 3,287 | 2,919 | 2,450 | |
| Income (loss) from operations | 447 | −568 | −1,208 | −1,790 | −1,439 | |
| Interest income | 71 | 70 | 78 | — | — | |
| Interest expense | −58 | −22 | −4 | — | — | |
| Other (expense) income, net | −43 | −13 | 308 | −224 | 16 | |
| Income (loss) before income taxes | 417 | −533 | −826 | −1,961 | — | |
| Income tax expense | 130 | 112 | 56 | 43 | 19 | |
| Net income (loss) | 287 | −645 | −882 | −2,004 | −1,458 | |
| Basic (in dollars per share) | 0.2 | −0.47 | −0.65 | −1.49 | −1.21 | |
| Diluted (in dollars per share) | 0.19 | −0.47 | −0.65 | −1.49 | −1.21 | |
| Weighted-average shares outstandingbasic (in shares) | 1,418 | 1,369 | 1,357 | 1,341 | 1,206 | |
| Weighted-average shares outstanding diluted (in shares) | 1,475 | 1,369 | 1,357 | 1,341 | 1,206 | |
| Basic (in dollars per share) | 2.63 | −6.12 | −8.45 | −19.43 | −15.71 | |
| Diluted (in dollars per share) | 2.53 | −6.12 | −8.45 | −19.43 | −15.71 | |
| Weighted-average ADSs outstanding, basic (in shares) | 109 | 105 | 104 | 103 | 93 | |
| Weighted-average ADSs outstanding, diluted (in shares) | 113 | 105 | 104 | 103 | 93 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 4,548 | 2,627 | 3,172 | 3,870 | 4,376 | |
| Accounts receivable, net | 865 | 676 | 358 | 173 | 483 | |
| Inventories, net | 608 | 495 | 416 | 282 | 243 | |
| Prepaid expenses and other current assets | 213 | 193 | 257 | 217 | 270 | |
| Total current assets | 6,234 | 3,992 | 4,203 | 5,207 | 7,614 | |
| Property, plant and equipment, net | 1,642 | 1,578 | 1,324 | 846 | 588 | |
| Operating lease right-of-use assets | 148 | 139 | 95 | 110 | 117 | |
| Intangible assets, net | 63 | 51 | 57 | 41 | 47 | |
| Other non-current assets | 102 | 160 | 125 | 176 | 163 | |
| Total non-current assets | 1,955 | 1,929 | 1,602 | 1,172 | 922 | |
| Total assets | 8,189 | 5,921 | 5,805 | 6,379 | 8,536 | |
| Accounts payable | 479 | 405 | 315 | 295 | 262 | |
| Accrued expenses and other payables | 1,109 | 804 | 694 | 467 | 558 | |
| Tax payable | 42 | 26 | 23 | 25 | 21 | |
| Operating lease liabilities, current portion | 21 | 18 | 22 | 24 | 22 | |
| Research and development cost share liability, current portion | 64 | 111 | 68 | 114 | 121 | |
| Sale of future royalty liability, current portion | 57 | 0 | — | — | — | |
| Short-term debt | 57 | 852 | 688 | 329 | 428 | |
| Total current liabilities | 1,829 | 2,215 | 1,810 | 1,469 | 1,600 | |
| Long-term debt | 962 | 166 | 198 | 209 | 202 | |
| Sale of future royalty liability, non-current portion | 850 | 0 | — | — | — | |
| Operating lease liabilities, non-current portion | 53 | 44 | 22 | 35 | 43 | |
| Deferred tax liabilities | 53 | 42 | 16 | 16 | 14 | |
| Research and development cost share liability, non-current portion | 0 | 54 | 171 | 180 | 270 | |
| Other long-term liabilities | 80 | 67 | 51 | 46 | 54 | |
| Total non-current liabilities | 1,999 | 374 | 458 | 527 | 803 | |
| Total liabilities | 3,827 | 2,589 | 2,268 | 1,996 | 2,403 | |
| Commitments and contingencies | — | — | — | — | — | |
| Ordinary shares, $0.0001 par value per share; 1,540,975,898 and 1,387,367,704 shares issued and 1,441,075,618 and 1,387,367,704 shares outstanding as of December 31, 2025 and 2024, respectively | 144,000 | 138,000 | 135,000 | 135,000 | 133,000 | |
| Additional paid-in capital | 12,759 | 12,088 | 11,599 | 11,541 | 11,191 | |
| Accumulated other comprehensive loss | −78 | −149 | −99 | −77 | 18 | |
| Accumulated deficit | −8,320 | −8,607 | −7,962 | −7,080 | −5,077 | |
| Total shareholders equity | 4,361 | 3,332 | 3,537 | 4,383 | 6,133 | |
| Total liabilities and shareholders equity | 8,189 | 5,921 | 5,805 | 6,379 | 8,536 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Depreciation and amortization expense | 142 | 172 | 88 | 66 | 46 | |
| Share-based compensation expense | 511 | 442 | 368 | 303 | 241 | |
| Acquired in-process research and development | 691,000 | 60 | 47 | 69 | 84 | |
| Amortization of research and development cost share liability | −101 | −73 | −55 | −96 | −112 | |
| Impairment of equity investments | 76 | 7 | 8 | — | — | |
| Loss on long-term investments | −596,000 | −17 | −9 | — | — | |
| Non-cash interest expense | 15 | 0 | 0 | — | — | |
| Deferred income tax expense | 9 | 26 | 689,000 | 2 | 3 | |
| Gain on BMS termination settlement | 0 | 0 | −363 | 0 | 0 | |
| Other items, net | −3 | 11 | −6 | 9 | 24 | |
| Accounts receivable | −165 | −329 | −188 | 304 | −423 | |
| Inventories | −93 | −91 | −141 | −57 | −153 | |
| Other assets | 37 | 45 | 12 | −3 | −107 | |
| Accounts payable | 80 | 121 | 21 | −4 | 20 | |
| Accrued expenses and other payables | 312 | 111 | 180 | 46 | 140 | |
| Deferred revenue | 1 | 633,000 | −256 | −152 | 408 | |
| Other liabilities | 19 | −15 | 587,000 | −1 | −3 | |
| Net cash provided by (used in) operating activities | 1,128 | −141 | −1,157 | −1,497 | −1,299 | |
| Purchases of property and equipment | −186 | −493 | −562 | −325 | −263 | |
| Purchase of in-process research and development | −61 | −32 | −15 | −144 | −9 | |
| Purchase of intangible assets | −20 | −5 | −19 | 0 | −43 | |
| Purchase of long-term investments | −12 | −19 | −15 | −16 | −44 | |
| Proceeds from sale or maturity of short-term investments | 3 | 3 | 673 | 1,564 | 3,147 | |
| Other investing activities | −1 | −3 | −2 | −1 | 0 | |
| Net cash (used in) provided by investing activities | −276 | −548 | 60 | 1,077 | 641 | |
| Proceeds from sale of future royalties | 911 | 0 | 0 | — | — | |
| Proceeds from long-term loan | 851 | 9 | 23 | 37 | 17 | |
| Repayment of long-term loan | −36 | −28 | −14 | 0 | 0 | |
| Proceeds from short-term loans | 234 | 868 | 662 | 314 | 406 | |
| Repayment of short-term loans | −1,045 | −704 | −310 | −417 | −322 | |
| Payments of debt issuance costs | −23 | 0 | 0 | — | — | |
| Payments of withholding taxes from share-based awards | −24 | 0 | 0 | — | — | |
| Proceeds from option exercises and employee share purchase plan | 196 | 45 | 56 | 47 | 93 | |
| Repayment of sale of future royalties liability | −4 | 0 | 0 | — | — | |
| Other financing activities | 0 | 3 | 0 | 0 | — | |
| Net cash provided by financing activities | 1,059 | 193 | 416 | −19 | 3,637 | |
| Effect of foreign exchange rate changes, net | 60 | −52 | −8 | −69 | 14 | |
| Net increase (decrease) in cash, cash equivalents, and restricted cash | 1,971 | −547 | −689 | −508 | 2,993 | |
| Interest paid | 52 | 51 | 20 | 25 | — | |
| Accruals for capital expenditures | 57 | 70 | 92 | 95 | 53 | |
| Purchase of in-process research and development included in accounts payable | 0 | 60 | 32 | 0 | 75 |