Keros Therapeutics, Inc.
Business
Keros Therapeutics, Inc. is a clinical-stage biopharmaceutical company developing engineered protein therapeutics that modulate signaling of the TGF-ß family to treat disorders of blood, bone, muscle, adipose and heart tissue. Its lead product candidates include elritercept for cytopenias in myelodysplastic syndromes and myelofibrosis, cibotercept for pulmonary arterial hypertension and cardiovascular disorders, and KER-065 for neuromuscular diseases such as Duchenne muscular dystrophy. The company operates organized franchises for pulmonary/cardiovascular, neuromuscular and hematology programs alongside discovery and preclinical pipelines. It pursues global development and commercialization through internal programs, third-party contract manufacturers and strategic collaborations and licensing arrangements with regional partners.
Summary from filing dated 2025-02-26
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Total revenue | 244 | 4 | 151,000 | 0 | 20 | |
| Research and development | −130 | −174 | −135 | −87 | −55 | |
| General and administrative | −47 | −41 | −35 | −28 | −21 | |
| Total operating expenses | −176 | −214 | −170 | −115 | −76 | |
| INCOME (LOSS) FROM OPERATIONS | 68 | −211 | −170 | −115 | −56 | |
| Research and development incentive income | 0 | 1 | 2 | 7 | 0 | |
| Dividend income | 25 | 23 | 15 | 4 | 27,000 | |
| Other expense, net | −539,000 | −954,000 | −206,000 | −613,000 | −383,000 | |
| Total other income, net | 24 | 24 | 17 | 10 | −360,000 | |
| Income (loss) before income taxes | 92 | −187 | −153 | −105 | −57 | |
| Income tax provision | −5 | −300,000 | 0 | 0 | −2 | |
| Net income (loss) | 87 | −187 | −153 | −105 | −59 | |
| Net income (loss) attributable to common stockholders - basic | 87 | −187 | −153 | −105 | −59 | |
| Net income (loss) attributable to common stockholders - diluted | 87 | −187 | −153 | −105 | −59 | |
| Weighted-average common stock outstanding - basic (in shares) | 37 | 37 | 29 | 25 | 23 | |
| Weighted-average common stock outstanding - diluted (in shares) | 38 | 37 | 29 | 25 | 23 | |
| Net income (loss) per share of common stock - basic (in dollars per share) | 2.34 | −5 | −5.2 | −4.15 | −2.52 | |
| Net income (loss) per share of common stock - diluted (in dollars per share) | 2.3 | −5 | −5.2 | −4.15 | −2.52 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 287 | 560 | 331 | 279 | 230 | |
| Accounts receivable | 4 | 3 | 143,000 | 0 | 18 | |
| Prepaid expenses and other current assets | 22 | 26 | 16 | 7 | 3 | |
| Current income tax receivable | 2 | 0 | — | — | — | |
| Total current assets | 315 | 589 | 347 | 286 | 251 | |
| Operating lease right-of-use assets | 17 | 19 | 15 | 16 | 1 | |
| Property and equipment, net | 4 | 4 | 4 | 2 | 1 | |
| Restricted cash | 1 | 1 | 1 | 1 | 1 | |
| Other long term assets | 0 | 2 | 2 | 2 | 82,000 | |
| TOTAL ASSETS | 338 | 616 | 370 | 307 | 255 | |
| Accounts payable | 2 | 5 | 5 | 3 | 4 | |
| Current portion of operating lease liabilities | 2 | 2 | 1 | 455,000 | 862,000 | |
| Accrued expenses and other current liabilities | 16 | 21 | 18 | 13 | 7 | |
| Total current liabilities | 20 | 27 | 24 | 17 | 12 | |
| Operating lease liabilities, net of current portion | 14 | 17 | 13 | 13 | 231,000 | |
| Total liabilities | 35 | 44 | 38 | 29 | 12 | |
| COMMITMENTS AND CONTINGENCIES (Note 14) | — | — | — | — | — | |
| Preferred stock, par value of $0.0001 per share; 10,000,000 shares authorized as of December 31, 2025 and 2024; no shares issued and outstanding | 0 | 0 | 0 | 0 | 0 | |
| Common stock, par value of $0.0001 per share; 200,000,000 shares authorized as of December 31, 2025 and December 31, 2024; 40,670,466 shares issued and 19,543,706 shares outstanding as of December 31, 2025 and 40,554,705 shares issued and outstanding as of December 31, 2024 | 4,000 | 4,000 | 3,000 | 2,000 | 2,000 | |
| Treasury stock, at cost; 21,126,760 and no shares as of December 31, 2025 and December 31, 2024, respectively | −385 | 0 | — | — | — | |
| Additional paid-in capital | 1,169 | 1,140 | 714 | 506 | 367 | |
| Accumulated deficit | −482 | −569 | −381 | −228 | −124 | |
| Total stockholders equity | 303 | 572 | 332 | 277 | 243 | |
| TOTAL LIABILITIES AND STOCKHOLDERS EQUITY | 338 | 616 | 370 | 307 | 255 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Depreciation expense | 2 | 1 | 815,000 | 674,000 | 378,000 | |
| Gain on disposal of fixed asset | −13,000 | 0 | 4,000 | 12,000 | 46,000 | |
| Stock-based compensation expense | 29 | 35 | 29 | 19 | 12 | |
| Non-cash lease expense | 2 | 2 | 2 | 941,000 | 520,000 | |
| Accounts receivable | −825,000 | −3 | −143,000 | 18 | −18 | |
| Prepaid expenses and other current assets | 4 | −10 | −9 | −3 | −2 | |
| Current income tax receivable | −2 | 0 | — | — | — | |
| Other assets | 2 | −4,000 | −478,000 | −2 | 0 | |
| Accounts payable | −3 | −249,000 | 2 | −408,000 | 1 | |
| Right-of-use assets and operating lease liabilities | −2 | −1 | 384,000 | −4 | −597,000 | |
| Accrued expenses and other current liabilities | −10 | 3 | 5 | 5 | 3 | |
| Net cash provided by (used in) operating activities | 108 | −161 | −125 | −70 | −62 | |
| Purchase of property and equipment | −2 | −2 | −2 | −1 | −1 | |
| Net cash used in investing activities | −2 | −2 | −2 | −1 | −1 | |
| Payment of issuance costs | 0 | −283,000 | 0 | 0 | 0 | |
| Payment of issuance costs associated with issuance of common stock under the ATM agreement | 0 | −171,000 | −94,000 | −87,000 | — | |
| Proceeds from issuance of common stock under the employee stock purchase plan | 138,000 | 0 | — | — | — | |
| Repurchase of treasury stock | −375 | 0 | — | — | — | |
| Payment of direct expenses associated with the treasury stock repurchase | −4 | 0 | — | — | — | |
| Short-swing profit settlement | 139,000 | 0 | — | — | — | |
| Proceeds from exercise of stock options | 150,000 | 12 | 3 | 818,000 | 379,000 | |
| Net cash provided by (used in) financing activities | −378 | 392 | 179 | 120 | 29 | |
| NET CHANGE IN CASH, CASH EQUIVALENTS AND RESTRICTED CASH | −273 | 229 | 52 | 49 | −35 | |
| Cash paid for taxes | 7 | 0 | — | — | — | |
| Property and equipment purchases in accounts payable and accrued expenses | 5,000 | 0 | 599,000 | 75,000 | 11,000 | |
| Treasury stock repurchase costs in accounts payable and accrued expenses | 6 | 0 | — | — | — | |
| Right-of-use assets obtained in exchange for operating lease obligation | 0 | 6 | 1 | 15 | 0 |