GRAIL, Inc.
Business
GRAIL, Inc. is a commercial-stage healthcare company that develops blood-based tests for early cancer detection using a proprietary targeted methylation platform. Its main product is Galleri, a multi-cancer early detection (MCED) screening test, and the company also offers a research-use-only targeted methylation platform and precision oncology applications and support services to guide follow-up care. Key business activities include commercial MCED screening, large-scale clinical and interventional studies, RUO offerings and biopharma partnerships, and laboratory operations. GRAIL distributes and markets its products primarily in the United States, participates in the UK NHS-Galleri trial, and uses channels including health systems, physicians, employers, payors, life insurers, telemedicine, and international distributors.
Summary from filing dated 2025-03-05
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 |
|---|---|---|---|---|---|
| Total revenue | 147 | 126 | 93 | 56 | |
| Cost of revenue amortization of intangible assets | 134 | 134 | 134 | — | |
| Research and development | 196 | 322 | 339 | 330 | |
| Sales and marketing | 117 | 154 | 162 | 122 | |
| General and administrative | 159 | 214 | 200 | 174 | |
| Goodwill and intangible assets impairment | 28 | 1,421 | 718 | 4,700 | |
| Total costs and operating expenses | 709 | 2,315 | 1,608 | 5,498 | |
| Loss from operations | −562 | −2,189 | −1,515 | −5,443 | |
| Interest income | 29 | 27 | 8 | 2 | |
| Other income (expense), net | −993,000 | 64,000 | −208,000 | −238,000 | |
| Total other income, net | 28 | 27 | 8 | 2 | |
| Loss before income taxes | −535 | −2,162 | −1,508 | −5,441 | |
| Benefit from income taxes | 126 | 135 | 42 | 42 | |
| Net loss | −408 | −2,027 | −1,466 | −5,399 | |
| Net loss per share Basic (in dollars per share) | −11.11 | −63.54 | −47.21 | −173.89 | |
| Net loss per shareDiluted (in dollars per share) | −11.11 | −63.54 | −47.21 | −173.89 | |
| Weighted-average shares of common stock used in computing net loss per sharebasic (in shares) | 37 | 32 | 31 | 31 | |
| Weighted-average shares of common stock used in computing net loss per sharediluted (in shares) | 37 | 32 | 31 | 31 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 |
|---|---|---|---|---|---|
| Cash and cash equivalents | 250 | 214 | 97 | 242 | |
| Short-term marketable securities | 655 | 549 | 0 | — | |
| Accounts receivable, net | 18 | 20 | 17 | — | |
| Supplies | 16 | 19 | 22 | — | |
| Prepaid expenses and other current assets | 15 | 17 | 20 | — | |
| Total current assets | 954 | 820 | 156 | — | |
| Property and equipment, net | 52 | 69 | 85 | — | |
| Operating lease right-of-use assets | 52 | 66 | 84 | — | |
| Restricted cash | 7 | 3 | 4 | — | |
| Intangible assets, net | 1,900 | 2,017 | 2,687 | — | |
| Other non-current assets | 7 | 8 | 8 | — | |
| Total assets | 2,922 | 2,983 | 3,914 | — | |
| Accounts payable | 2 | 5 | 20 | — | |
| Accrued liabilities | 64 | 57 | 74 | — | |
| Operating lease liabilities, current portion | 12 | 13 | 15 | — | |
| Other current liabilities | 2 | 2 | 809,000 | — | |
| Total current liabilities | 80 | 77 | 164 | — | |
| Operating lease liabilities, net of current portion | 43 | 55 | 70 | — | |
| Deferred tax liability, net | 219 | 346 | 33 | — | |
| Other non-current liabilities | 3 | 2 | 1 | — | |
| Total liabilities | 344 | 480 | 268 | — | |
| Commitments and contingencies (Note 10) | — | — | — | — | |
| Preferred stock, par value of $0.001 per share; 50,000,000 shares authorized, no shares issued and outstanding as of December 31, 2025 and December 31, 2024 | 0 | 0 | — | — | |
| Common stock $0.001 par value per share, 1,500,000,000 shares authorized, 40,331,360 and 33,893,409 shares issued and outstanding as of December 31, 2025 and December 31, 2024. | 40,000 | 34,000 | — | — | |
| Additional paid-in capital | 12,787 | 12,305 | — | — | |
| Accumulated other comprehensive income | 3 | 1 | 1 | — | |
| Accumulated deficit | −10,212 | −9,803 | −7,776 | — | |
| Total stockholders equity | 2,578 | 2,503 | — | — | |
| Total liabilities and stockholders equity | 2,922 | 2,983 | 3,914 | — |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 |
|---|---|---|---|---|---|
| Amortization of intangibles assets | 138 | 138 | 138 | — | |
| Depreciation | 18 | 20 | 20 | 16 | |
| Stock-based compensation expense | 58 | 86 | 97 | 76 | |
| Deferred income taxes | −126 | −134 | −38 | −39 | |
| Amortization of discount on marketable securities | −21 | −3 | 0 | 0 | |
| Credit loss expense | 332,000 | 0 | 0 | — | |
| Cash payment for equity awards | 0 | −54 | −77 | −41 | |
| Other | 1 | 276,000 | 3 | 1 | |
| Accounts receivable | 2 | −3 | −1 | −9 | |
| Supplies | 3 | 3 | −2 | −14 | |
| Operating lease right-of-use assets and liabilities, net | 1 | 2 | 7 | 5 | |
| Prepaid expenses and other assets | 3 | 2 | −908,000 | −11 | |
| Accounts payable | −3 | −15 | 3 | 2 | |
| Accrued and other liabilities | 6 | −13 | 2 | 12 | |
| Net cash used by operating activities | −299 | −577 | −596 | −561 | |
| Purchases of property and equipment | −909,000 | −5 | −13 | −23 | |
| Purchases of marketable securities | −1,308 | −546 | 0 | 0 | |
| Proceeds from maturities of marketable securities | 1,224 | 0 | 0 | — | |
| Net cash used in investing activities | −85 | −551 | −13 | −23 | |
| Issuance of common stock under ESPP | 5 | 0 | 0 | — | |
| Cash funding received from Illumina | 0 | 1,244 | 464 | 609 | |
| Other | 0 | 0 | −234,000 | −4 | |
| Net cash provided by financing activities | 423 | 1,244 | 464 | 605 | |
| Effect of exchange rate changes on cash, cash equivalents, and restricted cash | −147,000 | −62,000 | 305,000 | −511,000 | |
| Net increase (decrease) in cash, cash equivalents, and restricted cash | 39 | 116 | −145 | 20 | |
| Property and equipment included in accounts payable and accrued liabilities | −42,000 | 0 | −1 | −2 | |
| Operating cash flows from operating leases, net | −17 | −19 | −19 | −18 |