Black Diamond Therapeutics, Inc.
Business
Black Diamond Therapeutics, Inc. is a clinical-stage oncology company developing MasterKey therapies that target families of oncogenic mutations in patients with cancer. It develops orally available, brain-penetrant small-molecule MasterKey inhibitors, including lead candidate BDTX-1535 (EGFR), clinical-stage BDTX-4933 (RAF) and early-stage BDTX-4876, discovered using its proprietary MAP drug discovery engine. The company operates as a single business segment focused on discovery, preclinical and clinical development of mutant-selective kinase inhibitors and intellectual property protection. It conducts clinical trials and regulatory interactions primarily in the United States, pursues partnerships, and plans U.S. commercialization with third-party arrangements internationally.
Summary from filing dated 2025-03-06
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| License revenue | 70 | 0 | — | — | — | |
| Research and development | 34 | 51 | 59 | 64 | 97 | |
| General and administrative | 17 | 27 | 27 | 28 | 30 | |
| Impairment of right-of-use assets and property and equipment | 7 | 0 | — | — | — | |
| Total operating expenses | 57 | 79 | 86 | 93 | 127 | |
| Income (loss) from operations | 13 | −79 | −86 | −93 | −127 | |
| Interest income | 4 | 2 | 2 | 2 | 3 | |
| Other income (expense) | 6 | 7 | 2 | −354,000 | −2 | |
| Total other income (expense), net | 10 | 9 | 4 | 4 | 1 | |
| Net income (loss) | 22 | −70 | −82 | −91 | −126 | |
| Net income (loss) per share, basic (in dollars per share) | 0.39 | −1.27 | −1.88 | −2.52 | −3.47 | |
| Net income (loss) per share, diluted (in dollars per share) | 0.39 | −1.27 | −1.88 | −2.52 | −3.47 | |
| Weighted average common shares outstanding, basic (in shares) | 57 | 55 | 44 | 36 | 36 | |
| Weighted average common share outstanding, diluted (in shares) | 58 | 55 | 44 | 36 | 36 | |
| Change in unrealized (loss) gain on investments, net | 77,000 | 51,000 | 2 | −1 | −1 | |
| Comprehensive income (loss) | 22 | −70 | −81 | −93 | −127 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 21 | 36 | 56 | 34 | 66 | |
| Investments | 108 | 62 | 75 | 88 | 144 | |
| Prepaid expenses and other current assets | 4 | 3 | 3 | 5 | 6 | |
| Total current assets | 132 | 101 | 134 | 128 | 216 | |
| Property and equipment, net | 365,000 | 1 | 2 | 3 | 3 | |
| Restricted cash | 829,000 | 819,000 | 823,000 | 1 | 1 | |
| Right-of-use assets | 9 | 19 | 22 | 25 | 28 | |
| Other non-current assets | 73,000 | 249,000 | 0 | 0 | 16,000 | |
| Total assets | 143 | 123 | 159 | 156 | 248 | |
| Accounts payable | 579,000 | 4 | 2 | 2 | 4 | |
| Accrued expenses and other current liabilities | 15 | 17 | 17 | 13 | 20 | |
| Total current liabilities | 16 | 21 | 20 | 15 | 24 | |
| Non-current operating lease liability | 15 | 19 | 22 | 25 | 28 | |
| Total liabilities | 31 | 39 | 42 | 41 | 52 | |
| Commitments and contingencies (Note 12) | 0 | 0 | 0 | 0 | 0 | |
| Preferred stock, $0.0001 par value; 10,000,000 shares and 10,000,000 shares authorized at December 31, 2025 and 2024, respectively; no shares issued or outstanding at December 31, 2025 and 2024 | 0 | 0 | 0 | 0 | 0 | |
| Common stock; $0.0001 par value; 500,000,000 shares authorized at December 31, 2025 and 500,000,000 shares authorized at December 31, 2024; 57,138,057 shares issued and outstanding at December 31, 2025 and 56,644,655 shares issued and outstanding at December 31, 2024 | 8,000 | 7,000 | 7,000 | 5,000 | 5,000 | |
| Additional paid-in capital | 577 | 570 | 534 | 453 | 440 | |
| Accumulated other comprehensive income (loss) | 101,000 | 24,000 | −27,000 | −2 | −414,000 | |
| Accumulated deficit | −465 | −487 | −417 | −335 | −244 | |
| Total stockholders' equity | 112 | 83 | 117 | 116 | 196 | |
| Total liabilities and stockholders' equity | 143 | 123 | 159 | 156 | 248 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Stock-based compensation expense | 7 | 11 | 10 | 12 | 14 | |
| Depreciation expense | 325,000 | 343,000 | 437,000 | 508,000 | 205,000 | |
| (Accretion) amortization on investments | −1 | −4 | −1 | 536,000 | — | |
| Non-cash rent expense | 3 | 3 | 3 | 3 | 2 | |
| Gain on sale of investments | −74,000 | 0 | — | — | — | |
| Gain on sale of property and equipment | −27,000 | −94,000 | 0 | — | — | |
| Prepaid expenses and other current assets | −349,000 | 33,000 | 2 | 1 | −2 | |
| Other non-current assets | 176,000 | −249,000 | 0 | 16,000 | 90,000 | |
| Accounts payable | −3 | 2 | 597,000 | −2 | 2 | |
| Accrued expenses and other current liabilities | −1 | −756,000 | 4 | −6 | 9 | |
| Non-current operating lease liability | −4 | −3 | −3 | −3 | −2 | |
| Net cash provided by (used in) operating activities | 30 | −62 | −67 | −85 | −100 | |
| Proceeds from disposal of equipment | 27,000 | 94,000 | 95,000 | 9,000 | 0 | |
| Proceeds from sales and maturities of investments | 119 | 140 | 78 | 114 | 183 | |
| Purchases of investments | −164 | −123 | −62 | −60 | −50 | |
| Net cash provided by (used in) investing activities | −45 | 17 | 16 | 53 | 131 | |
| Proceeds from exercise of common stock options and ESPP, net of restricted stock surrendered for taxes | −146,000 | 1 | — | — | — | |
| Proceeds from issuance of common stock, net of issuance costs | 0 | 24 | 72 | 0 | — | |
| Net cash provided by (used in) financing activities | −146,000 | 26 | 72 | 177,000 | 729,000 | |
| Net (decrease) increase in cash and cash equivalents | −15 | −20 | 22 | −32 | 31 |