Beam Therapeutics Inc.
Business
Beam Therapeutics Inc. develops precision genetic medicines centered on its proprietary base editing platform to make single‑base changes without double‑stranded DNA breaks. It advances clinical‑stage product candidates and delivery technologies, including ex vivo hematopoietic stem cell therapies and in vivo lipid nanoparticle (LNP) formulations, supported by internal mRNA and cell therapy manufacturing. Its operations are organized around a research and development platform, therapeutic portfolios in hematology and genetic diseases, delivery and manufacturing capabilities, and strategic collaborations. The company conducts global clinical trials, supplies investigational material through internal facilities and CMOs, and pursues regulatory approvals in the U.S., EU, U.K., and other jurisdictions.
Summary from filing dated 2025-02-25
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| License and collaboration revenue | 140 | 64 | 378 | 61 | 52 | |
| Research and development | 410 | 368 | 437 | 312 | 387 | |
| General and administrative | 114 | 112 | 117 | 88 | 57 | |
| Total operating expenses | 523 | 479 | 554 | 399 | 444 | |
| Loss from operations | −384 | −416 | −176 | −338 | −392 | |
| Change in fair value of derivative liabilities | 700,000 | 2 | 8 | 24 | −1 | |
| Change in fair value of non-controlling equity investments | 4 | −14 | −19 | 20 | 18 | |
| Change in fair value of contingent consideration liabilities | 180,000 | 2 | 10 | — | — | |
| Gain on sale of equity method investment | 255 | — | — | −26 | — | |
| Interest and other income (expense), net | 44 | 49 | 47 | 15 | −9,000 | |
| Total other income (expense) | 304 | 39 | 45 | 78 | 22 | |
| Net loss before income taxes | −80 | −377 | −131 | −260 | −371 | |
| Provision for income taxes | 0 | −39,000 | −1 | −3 | 0 | |
| Net loss | −80 | −377 | −133 | −289 | −371 | |
| Unrealized gain (loss) on marketable securities | 432,000 | 75,000 | 3 | −2 | −41,000 | |
| Comprehensive loss | −80 | −377 | −129 | −291 | −371 | |
| Net loss per common share, basic | −0.81 | −4.58 | −1.72 | −4.13 | −5.77 | |
| Net loss per common share, diluted | −0.81 | −4.58 | −1.72 | −4.13 | −5.77 | |
| Weighted - average common shares outstanding, basic | 99 | 82 | 77 | 70 | 64 | |
| Weighted - average common shares outstanding, diluted | 99 | 82 | 77 | 70 | 64 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 295 | 282 | 436 | 233 | 560 | |
| Marketable securities | 950 | 569 | — | — | — | |
| Prepaid expenses and other current assets | 23 | 27 | 21 | 15 | 7 | |
| Total current assets | 1,269 | 878 | 1,211 | 1,093 | 1,273 | |
| Property and equipment, net | 105 | 111 | 125 | 116 | 84 | |
| Restricted cash | 7 | 8 | 9 | 13 | 13 | |
| Operating lease right-of-use assets | 101 | 105 | 113 | 119 | 103 | |
| Other assets | 634,000 | 1 | 2 | 2 | 2 | |
| Total assets | 1,481 | 1,104 | 1,460 | 1,342 | 1,474 | |
| Accounts payable | 10 | 4 | 2 | 9 | 7 | |
| Accrued expenses and other current liabilities | 55 | 47 | — | — | — | |
| Current portion of derivative liabilities | 8 | 8 | 11 | 18 | 42 | |
| Current portion of deferred revenue | 7 | 109 | 69 | 136 | 86 | |
| Current portion of lease liability | 14 | 13 | 13 | 10 | 8 | |
| Current portion of contingent consideration liabilities | 3 | — | — | — | — | |
| Total current liabilities | 97 | 182 | 206 | 224 | 213 | |
| Long-term lease liability | 140 | 148 | 160 | 169 | 135 | |
| Long-term portion of contingent consideration liabilities | 6 | 1 | 3 | 12 | 31 | |
| Long-term portion of deferred revenue | 0 | 33 | 110 | 202 | 262 | |
| Long-term portion of derivative liabilities | 0 | 5 | — | — | — | |
| Other liabilities | 173,000 | 504,000 | 298,000 | 1 | 3 | |
| Total liabilities | 243 | 370 | 478 | 608 | 648 | |
| Commitments and contingencies (See Note 9, License and other agreements and Note 10, Collaboration and license agreements) | — | — | — | — | — | |
| Preferred stock, $0.01 par value; 25,000,000 shares authorized, and no shares issued or outstanding at December 31, 2025 and December 31, 2024 respectively | — | — | — | — | — | |
| Common stock, $0.01 par value; 250,000,000 shares authorized, 101,748,962 and 83,633,069 issued and outstanding at December 31, 2025 and December 31, 2024, respectively | 1 | 836,000 | 816,000 | 712,000 | 684,000 | |
| Additional paid-in capital | 2,877 | 2,299 | 2,170 | 1,793 | 1,594 | |
| Accumulated other comprehensive (loss) income | 1 | 679,000 | 604,000 | −2 | −50,000 | |
| Accumulated deficit | −1,600 | −1,567 | −1,190 | −1,057 | −768 | |
| Total stockholders' equity | 1,238 | 734 | 981 | 733 | 827 | |
| Total liabilities and stockholders' equity | 1,481 | 1,104 | 1,460 | 1,342 | 1,474 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Net loss | −80 | −377 | −133 | −289 | −371 | |
| Depreciation and amortization | 22 | 22 | 20 | 14 | 7 | |
| Amortization of investment discount (premiums) | −16 | −23 | −30 | −9 | −75,000 | |
| In-process research and development charge | 15 | 0 | 0 | — | 155 | |
| Stock-based compensation expense | 94 | 121 | 99 | 84 | 44 | |
| Change in operating lease right-of-use assets | 10 | 10 | 10 | 8 | 9 | |
| Realized loss (gain) on sale of marketable securities | 399,000 | 0 | 0 | — | — | |
| Gain on sale of equity method investment | −255 | 0 | 0 | — | — | |
| Prepaid expenses and other current assets | 5 | −5 | −7 | −8 | 746,000 | |
| Accounts payable | 6 | 2 | −8 | 2 | 818,000 | |
| Accrued expenses and other liabilities | 8 | −58 | 68 | −17 | 44 | |
| Operating lease liabilities | −14 | −13 | −10 | 12 | 16 | |
| Deferred revenue | −135 | −37 | −160 | −36 | 348 | |
| Other long-term liabilities | −330,000 | 473,000 | −194,000 | −3 | 2 | |
| Net cash provided by (used in) operating activities | −345 | −347 | −149 | 23 | −66 | |
| Purchases of property and equipment | −15 | −9 | −34 | −49 | −47 | |
| Purchases of marketable securities | −1,210 | −486 | −984 | −1,617 | −777 | |
| Maturities of marketable securities | 842 | 680 | 1,090 | 1,205 | 529 | |
| Proceeds from sale of marketable securities | 6 | 0 | 0 | — | — | |
| Cash paid for acquisition, net | −78,000 | 0 | 0 | — | — | |
| Proceeds from sale of equity method investment | 255 | 0 | 0 | — | — | |
| Net cash provided by (used in) investing activities | −121 | 185 | 72 | −461 | −294 | |
| Proceeds from issuance of common shares and pre-funded warrants, net of issuance costs | 471 | 0 | 236 | — | — | |
| Proceeds from issuances of stock under ESPP | 3 | 3 | 3 | 3 | — | |
| Equipment financings, net | 0 | −485,000 | −2 | −2 | −2 | |
| Proceeds from exercise of stock options | 5 | 6 | 6 | 3 | 10 | |
| Proceeds from private stock issuance | 0 | 0 | 34 | — | — | |
| Net cash provided by (used in) financing activities | 478 | 8 | 276 | 112 | 756 | |
| Net change in cash, cash equivalents and restricted cash | 12 | −155 | 199 | −327 | 396 | |
| Cash paid for interest | 0 | 32,000 | 160,000 | 376,000 | 567,000 | |
| Property and equipment additions in accounts payable and accrued expenses | 1 | 834,000 | 1 | 6 | 9 | |
| Operating lease liabilities arising from obtaining right-of-use assets | 6 | −2 | 4 | 41 | — | |
| Contingent consideration liabilities assumed in acquisition | 8 | 0 | 0 | — | 37 | |
| Fair value of equity instruments issued in connection with acquisition | 7 | 0 | 0 | — | — |