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Werewolf Therapeutics, Inc.
HOWLCIK 0001785530NasdaqNon-AcceleratedSmaller ReportingEmerging GrowthPharmaceutical PreparationsDelawareFY ends Dec 31
Period
FY 2025
Revenue
—
Net Income
$-60.82M
Total Assets
$69.40M
Equity
$24.80M
Shares Out
48.60M
Op. Cash Flow
$-60.29M
Business
Werewolf Therapeutics, Inc. develops therapeutics that stimulate the immune system to treat cancer and other immune-mediated conditions. It engineers conditionally activated INDUKINE molecules using its PREDATOR protein engineering platform, with clinical-stage IL-2 (WTX-124) and IL-12 (WTX-330) candidates, preclinical candidates (WTX-712, WTX-518, WTX-921) and a licensed IFNα program (JZP898). Its business comprises platform discovery and engineering, preclinical development, clinical development and partnered programs. It advances systemically delivered candidates through clinical trials, leverages third-party manufacturers and partnerships, and targets the U.S. and other major pharmaceutical markets.
Summary from filing dated 2025-03-11
Financials
Consolidated Statement of Income
Year Ended · In millions, except per-share amounts
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Collaboration revenue | 0 | 2 | 20 | 16 | 0 | |
| Research and development | 45 | 56 | 42 | 54 | 35 | |
| General and administrative | 16 | 19 | 19 | 19 | 15 | |
| Total operating expenses | 61 | 75 | 60 | 72 | 50 | |
| Operating loss | −61 | −74 | −41 | −56 | −50 | |
| Interest income | 3 | 7 | 7 | 2 | — | |
| Interest expense | −5 | −5 | −3 | — | — | |
| Loss on extinguishment of debt | 0 | −553,000 | 0 | — | — | |
| Other income, net | 2 | 2 | −1 | 338,000 | — | |
| Total other (expense) income | −145,000 | 3 | 3 | 2 | 104,000 | |
| Net loss | −61 | −71 | −37 | −54 | −50 | |
| Net loss per common share, basic (in usd per share) | −1.32 | −1.63 | −1.05 | −1.86 | −10.94 | |
| Net loss per common share, diluted (in usd per share) | −1.33 | −1.63 | −1.05 | −1.86 | −10.94 | |
| Weighted average common shares outstanding, basic (in shares) | 46 | 43 | 36 | 29 | 18 | |
| Weighted average common shares outstanding, diluted (in shares) | 47 | 44 | 36 | 29 | 18 |
Consolidated Balance Sheet
As of · In millions, except per-share amounts
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 57 | 111 | 134 | 129 | 158 | |
| Prepaid expenses and other current assets | 2 | 2 | 3 | 4 | 4 | |
| Total current assets | 59 | 113 | 138 | 140 | 161 | |
| Property and equipment, net | 5 | 6 | 8 | 9 | 3 | |
| Restricted cash and cash equivalents | 901,000 | 1 | 21 | 1 | 1 | |
| Operating lease right of use asset | 5 | 6 | 7 | 8 | 13 | |
| Other assets | 5,000 | 320,000 | 594,000 | 1 | 649,000 | |
| Total assets | 69 | 127 | 175 | 160 | 179 | |
| Accounts payable | 754,000 | 3 | 1 | 1 | 2 | |
| Accrued expenses and other current liabilities | 5 | 11 | 9 | 14 | 9 | |
| Operating lease liability, current | 2 | 2 | 2 | 2 | 1 | |
| Note payable, current, net of discount and issuance costs | 28 | 0 | 7 | 0 | — | |
| Total current liabilities | 36 | 15 | 19 | 24 | 12 | |
| Operating lease liability, net of current portion | 8 | 9 | 11 | 13 | 15 | |
| Note payable, net of discount, issuance costs, and current portion | 0 | 26 | 33 | 0 | — | |
| Derivative liability | 759,000 | 3 | 0 | — | — | |
| Total liabilities | 45 | 54 | 63 | 38 | 26 | |
| Commitments and contingencies | — | — | — | — | — | |
| Preferred stock, $0.0001 par value, 5,000,000 shares authorized as of December 31, 2025 and 2024; no shares issued or outstanding as of December 31, 2025 and 2024 | 0 | 0 | 0 | 0 | 0 | |
| Common stock, $0.0001 par value, 200,000,000 shares authorized as of December 31, 2025 and 2024; 48,596,817 and 44,827,159 shares issued and outstanding as of December 31, 2025 and 2024, respectively | 5,000 | 5,000 | 4,000 | 3,000 | 2,000 | |
| Additional paid-in capital | 500 | 488 | 455 | 429 | 406 | |
| Accumulated deficit | −475 | −415 | −344 | −307 | −253 | |
| Total stockholders equity | 25 | 73 | 111 | 122 | 153 | |
| Total liabilities and stockholders equity | 69 | 127 | 175 | 160 | 179 | |
| Common stock outstanding (in shares) | 49 | 45 | 39 | 31 | 27 |
Consolidated Statement of Cash Flows
Year Ended · In millions, except per-share amounts
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Stock-based compensation expense | 6 | 9 | 8 | 7 | 4 | |
| Depreciation expense | 2 | 2 | 2 | 1 | 200,000 | |
| Non-cash interest expense | 2 | 1 | 273,000 | 0 | — | |
| Non-cash lease expense | 785,000 | 887,000 | 2 | 1 | 519,000 | |
| Change in fair value of derivative liability | −2 | −2 | 0 | — | — | |
| Prepaid expenses and other assets | 850,000 | 669,000 | 1 | −262,000 | −3 | |
| Other receivables | 0 | 1 | 6 | −7 | 0 | |
| Accounts payable, accrued expenses and other liabilities | −7 | 3 | −4 | 3 | — | |
| Deferred revenue | 0 | −1 | −6 | 8 | 0 | |
| Operating lease liability | −2 | −2 | −2 | −977,000 | — | |
| Net cash used in operating activities | −60 | −56 | −33 | −41 | −43 | |
| Purchases of property and equipment | 0 | −254,000 | −769,000 | −4 | −498,000 | |
| Net cash used in investing activities | 0 | −254,000 | −769,000 | −4 | −498,000 | |
| Proceeds from at the market offering of common stock, net of issuance costs | 6 | 24 | 18 | 16 | 0 | |
| Proceeds from drawdown of term loans | 0 | 30 | 40 | 0 | — | |
| Payment of debt issuance costs | 0 | −673,000 | 0 | — | — | |
| Repayment of term loan | 0 | −40 | 0 | — | — | |
| Proceeds from issuances under Employee Stock Purchase Plan | 89,000 | 142,000 | 93,000 | 0 | — | |
| Proceeds from stock option exercises | 0 | 35,000 | 7,000 | 254,000 | 205,000 | |
| Net cash provided by financing activities | 6 | 13 | 58 | 16 | 109 | |
| Net decrease in cash, cash equivalents and restricted cash and cash equivalents | −54 | −43 | 25 | −28 | 66 | |
| Cash paid for interest | 3 | 3 | 3 | 0 | — | |
| Issuance costs in accounts payable and accrued expenses | 120,000 | 84,000 | 36,000 | 4,000 | 0 | |
| Fair value of derivative liability issued with term loan | 0 | 4 | 0 | — | — |
Filings
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