Cullinan Therapeutics, Inc.
Business
Cullinan Therapeutics, Inc. is a clinical-stage biopharmaceutical company discovering and developing targeted immunology and oncology therapeutics. Its main product candidates include CLN-978 (CD19xCD3 T cell engager), CLN-619 (anti‑MICA/B monoclonal antibody), zipalertinib (EGFRex20 small‑molecule inhibitor), CLN-049 (FLT3xCD3 bispecific) and CLN-617 (IL‑2/IL‑12 fusion protein). The business is organized around two key segments—immunology and oncology—with programs advanced through clinical development and strategic collaborations. Cullinan conducts global clinical trials and relies on partnerships and contract manufacturers across North America, Europe and Asia for development, manufacturing and distribution.
Summary from filing dated 2025-02-27
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Research and development | 187 | 143 | 148 | 92 | 58 | |
| General and administrative expense | 54 | 54 | 42 | 40 | 29 | |
| Total operating expenses | 242 | 197 | 191 | 132 | 87 | |
| Loss from operations | −242 | −197 | −191 | 145 | −68 | |
| Interest income | 22 | 30 | 22 | 7 | 477,000 | |
| Other income (expense), net | −443,000 | −199,000 | 239,000 | 57,000 | −8,000 | |
| Net loss before income taxes | −220 | −167 | −169 | 151 | −67 | |
| Effective tax rate | 0 | 117,000 | −14 | 42 | 0 | |
| Net loss | −220 | −168 | −155 | 109 | −67 | |
| Net loss attributable to noncontrolling interests | 0 | −192,000 | −2 | −2 | −2 | |
| Net loss attributable to Cullinan | −220 | −167 | −153 | 111 | −66 | |
| Unrealized gain (loss) on investments | 1 | −4,000 | 2 | −2 | −836,000 | |
| Comprehensive loss | −219 | −168 | −153 | 107 | −68 | |
| Comprehensive loss attributable to noncontrolling interests | 0 | −192,000 | −2 | −2 | −2 | |
| Comprehensive loss attributable to Cullinan | −219 | −167 | −151 | 109 | −66 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 88 | 83 | 98 | 156 | 60 | |
| Short-term investments | 290 | 316 | 369 | 311 | 231 | |
| Prepaid expenses and other current assets | 9 | 16 | 13 | 7 | 6 | |
| Total current assets | 387 | 415 | 480 | 474 | 297 | |
| Property and equipment, net | 421,000 | 683,000 | 989,000 | 1 | 77,000 | |
| Operating lease right-of-use assets | 3 | 2 | 3 | 4 | 1 | |
| Other assets | 297,000 | 366,000 | 459,000 | 459,000 | 147,000 | |
| Long-term investments | 58 | 204 | 0 | 81 | 140 | |
| Total assets | 448 | 622 | 484 | 561 | 437 | |
| Accounts payable | 841,000 | 2 | 2 | 3 | 3 | |
| Accrued expenses and other current liabilities | 36 | 28 | 24 | 14 | 9 | |
| Operating lease liabilities, current | 780,000 | 1 | 1 | 1 | — | |
| Total current liabilities | 38 | 31 | 28 | 22 | 12 | |
| Operating lease liabilities, net of current portion | 2 | 849,000 | 2 | 4 | — | |
| Total liabilities | 40 | 31 | 30 | 26 | 12 | |
| Commitments and contingencies (Note 11) | — | — | — | — | — | |
| Preferred stock, $0.0001 par value, 10,000,000 shares authorized as of December 31, 2025 and 2024; 555,935 and 647,500 shares issued and outstanding as of December 31, 2025 and 2024, respectively. | 0 | 0 | 0 | 0 | — | |
| Common stock, $0.0001 par value, 150,000,000 shares authorized as of December 31, 2025 and 2024; 60,244,136 and 58,510,610 shares issued and outstanding as of December 31, 2025 and 2024, respectively. | 6,000 | 6,000 | 4,000 | 5,000 | 4,000 | |
| Additional paid-in capital | 996 | 959 | 655 | 585 | 585 | |
| Accumulated other comprehensive gain (loss) | 1 | −133,000 | −129,000 | −3 | −838,000 | |
| Accumulated deficit | −588 | −368 | −201 | −48 | −159 | |
| Total Cullinan stockholders' equity | 409 | 590 | 454 | 535 | 425 | |
| Noncontrolling interests | 0 | 0 | 192,000 | 0 | 403,000 | |
| Total stockholders' equity | 409 | 590 | 454 | 535 | 425 | |
| Total liabilities and stockholders' equity | 448 | 622 | 484 | 561 | 437 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Equity-based compensation expense | 36 | 38 | 30 | 28 | 24 | |
| Accretion on marketable securities | −6 | −15 | −10 | 1 | 3 | |
| Depreciation and amortization | 311,000 | 306,000 | 310,000 | 93,000 | 53,000 | |
| Prepaid expenses and other current assets | 7 | −2 | −6 | −1 | −3 | |
| Accounts payable | −839,000 | −812,000 | −167,000 | −509,000 | −5 | |
| Accrued expenses and other liabilities | 8 | 3 | 10 | 9 | 5 | |
| Net cash used in operating activities | −176 | −145 | −134 | −127 | −43 | |
| Maturities of marketable securities | 417 | 585 | 409 | 353 | 192 | |
| Purchase of marketable securities | −237 | −721 | −373 | −378 | −526 | |
| Purchase of property and equipment | −49,000 | 0 | −208,000 | −1 | 0 | |
| Net cash provided by (used in) investing activities | 180 | −136 | 36 | 249 | −334 | |
| Issuance of common stock under equity-based compensation plans | 1 | 8 | 538,000 | 6 | — | |
| Issuance of common stock and pre-funded warrants, net of issuance costs | 0 | 263 | 38 | 0 | 3 | |
| Net cash provided by financing activities | 1 | 266 | 41 | −26 | 269 | |
| Net decrease in cash and cash equivalents | 5 | −15 | −58 | 96 | −108 | |
| Cash refunded for income taxes | −3 | −2 | −4 | 38 | 0 |