AN2 Therapeutics, Inc.
Business
AN2 Therapeutics is a clinical-stage biopharmaceutical company focused on discovering and developing novel small-molecule therapeutics derived from its proprietary boron chemistry platform. The company's pipeline spans hematologic diseases, infectious diseases, and oncology, with lead candidates including epetraborole for polycythemia vera and Mycobacterium abscessus lung disease, and AN2-502998 for Chagas disease. AN2 operates through licensed intellectual property, relies on third-party contract manufacturers for all drug production, and funds certain development programs through non-dilutive grant agreements.
Summary from 10-K filed 2026-03-17
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Research and development | 25 | 40 | 55 | 29 | 16 | |
| General and administrative | 13 | 14 | 15 | 13 | 5 | |
| Restructuring charges | — | 2 | — | — | — | |
| Total operating expenses | 38 | 57 | 70 | 42 | 22 | |
| Loss from operations | −38 | −57 | −70 | −42 | −22 | |
| Interest income | 3 | 5 | 5 | — | — | |
| Other income | 1,000 | 1,000 | 43,000 | 1 | −38,000 | |
| Net loss attributable to common stockholders | −35 | −51 | −65 | −43 | −28 | |
| Net loss per share attributable to common stockholders, basic | −1.16 | −1.72 | −2.74 | −2.79 | −10.64 | |
| Net loss per share attributable to common stockholders, diluted | −1.16 | −1.72 | −2.74 | −2.79 | −10.64 | |
| Weighted-average number of shares used in computing net loss per share, basic | 30 | 30 | 24 | 15 | 3 | |
| Weighted-average number of shares used in computing net loss per share, diluted | 30 | 30 | 24 | 15 | 3 | |
| Unrealized gain (loss) on investments | 26,000 | −244,000 | 649,000 | −347,000 | −27,000 | |
| Comprehensive loss | −35 | −52 | −64 | −41 | −22 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 20 | 21 | 16 | 27 | 12 | |
| Short-term investments | 38 | 62 | 92 | 69 | 46 | |
| Prepaid expenses and other current assets | 2 | 3 | 3 | 3 | 2 | |
| Total current assets | 60 | 86 | 111 | 99 | 60 | |
| Long-term investments | 2 | 5 | 27 | 3 | 3 | |
| Other assets, long-term | 0 | 804,000 | 1 | 720,000 | — | |
| Total assets | 62 | 92 | 139 | 103 | 65 | |
| Accounts payable | 3 | 3 | 3 | 2 | 1 | |
| Accrued compensation | 2 | 2 | 4 | 2 | 916,000 | |
| Accrued liabilities | 2 | 4 | 7 | 3 | 1 | |
| Other current liabilities | 1 | 791,000 | 666,000 | — | — | |
| Total current liabilities | 9 | 10 | 14 | 7 | 3 | |
| Other non-current liabilities | 170,000 | 0 | — | — | — | |
| Total liabilities | 9 | 10 | 14 | 7 | 3 | |
| Commitments and contingencies (Note 7) | — | — | — | — | — | |
| Preferred stock, $0.00001 par value; 10,000,000 shares authorized at December 31, 2025 and December 31, 2024; no shares issued and outstanding at December 31, 2025 and December 31, 2024 | — | — | — | — | — | |
| Common stock, $0.00001 par value; 500,000,000 shares authorized at December 31, 2025 and December 31, 2024; 27,413,171 and 29,919,634 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively | — | — | — | — | — | |
| Additional paid-in capital | 294 | 288 | 279 | 185 | — | |
| Accumulated other comprehensive gain | 57,000 | 31,000 | 275,000 | −374,000 | −27,000 | |
| Accumulated deficit | −241 | −206 | −154 | −90 | −47 | |
| Total stockholders' equity | 53 | 82 | 125 | 95 | −47 | |
| Total liabilities and stockholders' equity | 62 | 92 | 139 | 103 | 65 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Net Loss | −35 | −51 | −65 | −41 | −22 | |
| Stock-based compensation expense | 6 | 8 | 8 | 4 | 974,000 | |
| Net accretion of discount on investments | −1 | −3 | −3 | −692,000 | 53,000 | |
| Prepaid expenses and other assets | 2 | 807,000 | −1 | −2 | −1 | |
| Accounts payable | −296,000 | 641,000 | 553,000 | 2 | 417,000 | |
| Accrued compensation | 742,000 | −2 | 2 | 1 | 490,000 | |
| Accrued liabilities | −2 | −2 | 4 | 2 | 512,000 | |
| Other current liabilities | 438,000 | 126,000 | 666,000 | — | — | |
| Other non-current liabilities | 170,000 | — | — | — | — | |
| Net cash used in operating activities | −30 | −49 | −53 | −33 | −20 | |
| Purchases of investments | −46 | −47 | −132 | −94 | −77 | |
| Maturities of investments | 75 | 101 | 89 | 72 | 27 | |
| Net cash provided by investing activities | 28 | 55 | −43 | −22 | −50 | |
| Proceeds from issuance of common stock under the ESPP | 86,000 | 147,000 | 366,000 | — | — | |
| Proceeds from exercise of stock options | 27,000 | 225,000 | 99,000 | — | 11,000 | |
| Net cash provided by financing activities | 113,000 | 372,000 | 85 | 70 | 79 | |
| Net (decrease) increase in cash and cash equivalents | −1 | 6 | −12 | 15 | 8 |
Filings
Material Events
Insiders
Institutional Holders
Frequently asked questions
What is AN2 Therapeutics, Inc.'s CIK number?
AN2 Therapeutics, Inc.'s SEC CIK number is 0001880438 (1880438). The CIK (Central Index Key) is the permanent identifier the SEC assigns to every EDGAR filer — unlike a ticker symbol, it never changes.
Where can I find AN2 Therapeutics, Inc.'s SEC filings?
All of AN2 Therapeutics, Inc.'s EDGAR filings — 10-K annual reports, 10-Q quarterly reports, 8-K material events, and insider transactions — are listed on this page, sourced live from SEC EDGAR.
When did AN2 Therapeutics, Inc. last report earnings?
AN2 Therapeutics, Inc. (ANTX) most recently filed an earnings 8-K with the SEC on May 11, 2026, furnishing its results under Item 2.02 (Results of Operations and Financial Condition). The earnings press release is attached to that filing (accession 0001193125-26-216752). This is AN2 Therapeutics, Inc.'s most recent earnings filing of record — not a forecast of its next earnings date.
What is AN2 Therapeutics, Inc.'s most recent earnings 8-K?
AN2 Therapeutics, Inc.'s latest earnings 8-K (Item 2.02) was filed May 11, 2026 under accession 0001193125-26-216752. It carries the quarterly or annual earnings press release — the earliest official, SEC-filed version of the results.
View AN2 Therapeutics, Inc.'s latest earnings 8-K →
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