Segment ReportingThe Company has one reportable segment.
The Company’s Chief Operating Decision Maker (the “CODM”), its Chief Executive Officer, manages the Company’s operations on a consolidated basis for the purposes of allocating resources, making operating decisions and evaluating performance. When evaluating the Company’s financial performance, the CODM regularly reviews total expenses by expense category and the CODM makes decisions using this information on a consolidated basis. There are no other measures of profitability used by the CODM, other than those disclosed in these consolidated financial statements.
The table below is a summary of the significant segment expenses (in thousands) provided to our CODM on a regular basis:
| | | | | | | | | | | | | | |
| | | | |
| | Years Ended December 31, |
| | 2024 | | 2023 |
Drug creation programs and platform (1) | | $ | 16,344 | | | $ | 13,714 | |
External pre-clinical and clinical development (2) | | 9,336 | | | — | |
Personnel (3) | | 38,558 | | | 42,165 | |
| Stock-based compensation | | 19,469 | | | 11,454 | |
| General & administrative | | 14,947 | | | 18,100 | |
| Asset and goodwill impairment | | 1,379 | | | 21,801 | |
| Depreciation and amortization | | 13,389 | | | 13,999 | |
| Total operating expenses | | $ | 113,422 | | | $ | 121,233 | |
| | | | |
(1) “Drug creation programs and platform” consists of research and development costs incurred related to the Company’s internally developed programs and drug creation partnership programs for activities prior to the nomination of a development candidate and the continued development of the Company’s Integrated Drug Creation platform.
(2) “External preclinical and clinical development” expense consists of external costs incurred following the Company’s nomination of a development candidate, including all subsequent contract research services, contract manufacturing, consulting fees, and other external costs related to preclinical and clinical development.
(3) “Personnel” expense consists of all employee wages, taxes, benefits, other employee related costs.
See the consolidated statement of operations and comprehensive loss for revenues and net losses associated with the reportable segment.
About Segments Disclosures
Segment disclosures break a company into its reportable operating units, revealing revenue, profit, and asset allocation that consolidated financial statements obscure. Under ASC 280, segments must match how the chief operating decision maker views the business, providing a window into internal management structure and resource allocation priorities.
Key signals: compare segment margins to identify which units drive profitability and which destroy value. Watch for changes in the number of reportable segments — segment aggregation or disaggregation often coincides with strategic shifts or attempts to obscure declining performance. Intersegment elimination patterns reveal internal pricing practices. The reconciliation between segment totals and consolidated figures exposes corporate overhead allocation and unallocated items. Geographic revenue concentration highlights regulatory and currency exposure. Compare segment-level capital expenditure against segment revenue to assess where management is investing for future growth versus harvesting existing assets.