17. Segment Reporting

The Company’s operations are organized and reported as a single reportable segment, which includes all activities related to the discovery, development, and commercialization of allogeneic gamma delta T cell therapies for autoimmune diseases and cancer. The Company’s Chief Executive Officer, who is the chief operating decision maker, reviews financial information on an aggregate basis for purposes of allocating resources and evaluating financial performance. This presentation is consistent with how the Company’s CODM, its Chief Executive Officer, assesses the performance of the Company and makes operating decisions on a consolidated basis. The accounting policies of the consolidated segment are the same as those described in the summary of significant accounting policies (refer to Note 2). The CODM assesses performance and decides how to allocate resources based on consolidated net loss that also is reported on the consolidated statements of operations and comprehensive loss as net loss. The CODM uses consolidated net loss to monitor budget versus actual results, assess cash runway, and benchmark against the Company’s competitors. The measure of segment assets is reported on the consolidated balance sheets as total assets. The Company’s assets are primarily held in the United States.

The following table sets forth the Company’s segment information (in thousands):

 

Twelve Months Ended December 31,

 

 

 

2025

 

 

2024

 

 

External program expenses for product candidates

 

 

 

 

 

 

Prula-cel

$

17,038

 

 

$

17,756

 

 

ADI-270

 

9,440

 

 

 

4,474

 

 

ADI-212

 

2,181

 

 

 

 

 

Other programs(1)

 

 

 

 

1,191

 

 

Total external program expenses for product candidates

 

28,659

 

 

 

23,421

 

 

Non-program specific expenses(2)

 

11,300

 

 

 

12,085

 

 

Personnel-related expenses (including non-cash stock-based compensation)(3)

 

53,194

 

 

 

62,163

 

 

Depreciation

 

6,381

 

 

 

6,468

 

 

Professional services and consulting fees

 

8,050

 

 

 

7,339

 

 

Facilities and infrastructure expenses

 

8,154

 

 

 

8,560

 

 

Other segment expense(4)

 

6,376

 

 

 

7,579

 

 

Interest income

 

(5,777

)

 

 

(10,714

)

 

Other expense, net

 

466

 

 

 

221

 

 

Income tax provision

 

 

 

 

 

 

Segment net loss

$

116,803

 

 

$

117,122

 

 

(1)
Relates to programs that have been discontinued or are currently in the research stage.
(2)
Relates to platform research and development expenses which are not attributed to specific programs.
(3)
Relates to personnel-related expenses, including non-cash stock-based compensation for the years ended December 31, 2025 and 2024 of $14.3 million and $22.2 million, respectively.
(4)
Relates to other expenses primarily for software subscriptions and licenses, office expenses, travel and entertainment, director compensation and recruiting fees.

Historical Timeline

Fiscal YearFiled
2025Mar 12, 2026Showing above
2024Mar 6, 2025

About Segments Disclosures

Segment disclosures break a company into its reportable operating units, revealing revenue, profit, and asset allocation that consolidated financial statements obscure. Under ASC 280, segments must match how the chief operating decision maker views the business, providing a window into internal management structure and resource allocation priorities.

Key signals: compare segment margins to identify which units drive profitability and which destroy value. Watch for changes in the number of reportable segments — segment aggregation or disaggregation often coincides with strategic shifts or attempts to obscure declining performance. Intersegment elimination patterns reveal internal pricing practices. The reconciliation between segment totals and consolidated figures exposes corporate overhead allocation and unallocated items. Geographic revenue concentration highlights regulatory and currency exposure. Compare segment-level capital expenditure against segment revenue to assess where management is investing for future growth versus harvesting existing assets.