17. Segment Reporting

The Company operates in a single operating segment and has one reportable segment, which includes all activities related to the discovery, development, and manufacturing of its product candidates. The determination of a single segment is consistent with the consolidated financial information regularly provided to the Company's chief operating decision maker ("CODM"). The Company’s CODM is its chief executive officer. The CODM uses consolidated net loss for purpose of assessing performance, making operating decisions and allocating resources. The measurement of segment assets is reported on the balance sheet as total consolidated assets.

The table below provides information about the Company’s segment (in thousands):

 

Year Ended December 31,

 

 

2025

 

 

2024

 

 

2023

 

Collaboration revenue

$

22,286

 

 

$

107,936

 

 

$

110,319

 

Operating expenses:

 

 

 

 

 

 

Research and development

 

 

 

 

 

 

 

 

anito-cel in rrMM

 

32,719

 

 

 

50,141

 

 

 

73,530

 

ACLX-002

 

9,153

 

 

 

14,294

 

 

 

5,667

 

Other research and development costs

 

27,132

 

 

 

23,339

 

 

 

6,640

 

Internal costs [1]

 

88,607

 

 

 

69,319

 

 

 

48,012

 

General and administrative

 

117,758

 

 

 

88,414

 

 

 

66,350

 

Total operating expenses

 

275,369

 

 

 

245,507

 

 

 

200,199

 

Loss from operations

 

(253,083

)

 

 

(137,571

)

 

 

(89,880

)

       Interest and other income (expense), net

 

24,218

 

 

 

33,322

 

 

 

23,695

 

       Interest expense

 

 

 

 

(1,030

)

 

 

(3,842

)

Total other income, net

 

24,218

 

 

 

32,292

 

 

 

19,853

 

       Income tax expense

 

(69

)

 

 

(2,069

)

 

 

(663

)

Net loss

$

(228,934

)

 

$

(107,348

)

 

$

(70,690

)

 

[1]Internal costs primarily consist of employee-related costs, including salaries, related benefits, and share-based compensation expense, as well as facility and depreciation expense.

Historical Timeline

Fiscal YearFiled
2025Feb 26, 2026Showing above
2024Feb 27, 2025

About Segments Disclosures

Segment disclosures break a company into its reportable operating units, revealing revenue, profit, and asset allocation that consolidated financial statements obscure. Under ASC 280, segments must match how the chief operating decision maker views the business, providing a window into internal management structure and resource allocation priorities.

Key signals: compare segment margins to identify which units drive profitability and which destroy value. Watch for changes in the number of reportable segments — segment aggregation or disaggregation often coincides with strategic shifts or attempts to obscure declining performance. Intersegment elimination patterns reveal internal pricing practices. The reconciliation between segment totals and consolidated figures exposes corporate overhead allocation and unallocated items. Geographic revenue concentration highlights regulatory and currency exposure. Compare segment-level capital expenditure against segment revenue to assess where management is investing for future growth versus harvesting existing assets.