(22) Segment and Geographic Information

Segments

We are managed and currently operate as two segments. However, we have concluded that our operating segments meet the criteria required by ASC 280 to be aggregated into one reportable segment. Our operating segments have similar economic characteristics and are similar with respect to the five qualitative characteristics specified in ASC 280. Accordingly, we have one reportable segment. Our one reportable segment is focused on the discovery, development and manufacturing of a comprehensive pipeline of immunological agents designed to expand patient populations benefiting from cancer immunotherapy.

Our Chief Executive Officer (“CEO”) serves as our Chief Operating Decision Maker (“CODM”) and is responsible for reviewing company performance and making decisions regarding resource allocation. Our CODM evaluates company performance based on net loss, as included in the Consolidated Statements of Operations and Comprehensive Income (Loss), ensuring resource

allocation decisions support company goals. The measure of segment assets is total assets, as included in the Consolidated Balance Sheets. Refer to the consolidated financial statements for other financial information regarding our single reportable segment.

The following table presents selected financial information related to our single reportable segment for the years ended December 31, 2025, 2024, and 2023 (in thousands):

 

 

Year Ended December 31,

 

 

 

2025

 

 

2024

 

 

2023

 

Revenues

 

$

114,196

 

 

$

103,463

 

 

$

156,314

 

 

 

 

 

 

 

 

 

 

 

Operating expenses:

 

 

 

 

 

 

 

 

 

External expenses

 

 

(70,213

)

 

 

(133,683

)

 

 

(202,205

)

Payroll related expenses

 

 

(39,664

)

 

 

(61,814

)

 

 

(75,955

)

Other operating expenses

 

 

(24,488

)

 

 

(28,441

)

 

 

(37,703

)

Operating loss

 

 

(20,169

)

 

 

(120,475

)

 

 

(159,549

)

 

 

 

 

 

 

 

 

 

 

Other income (expense):

 

 

 

 

 

 

 

 

 

Interest expense

 

 

(55,618

)

 

 

(120,421

)

 

 

(103,859

)

Interest income

 

 

345

 

 

 

2,795

 

 

 

5,934

 

Other income

 

 

72,359

 

 

 

5,830

 

 

 

37

 

Net loss

 

$

(3,083

)

 

$

(232,271

)

 

$

(257,437

)

In the table above, “Other operating expenses” includes items such as depreciation and amortization expense, stock-based compensation expense, fair value adjustments and expenses related to certain foreign subsidiaries.

Geographic Information

The following is geographical information regarding our revenues for the years ended December 31, 2025, 2024 and 2023 and our long-lived assets as of December 31, 2025 and 2024 (in thousands):

 

 

2025

 

 

2024

 

 

2023

 

Revenue:

 

 

 

 

 

 

 

 

 

United States

 

$

113,160

 

 

$

101,460

 

 

$

153,336

 

Rest of world

 

 

1,036

 

 

 

2,003

 

 

 

2,978

 

 

 

$

114,196

 

 

$

103,463

 

 

$

156,314

 

In the table above, revenue by geographic region is allocated based on the domicile of our respective business operations.

 

 

2025

 

 

2024

 

Long-lived Assets:

 

 

 

 

 

 

United States

 

$

17,602

 

 

$

122,887

 

Rest of world

 

 

1,175

 

 

 

3,034

 

Total

 

$

18,777

 

 

$

125,921

 

In the table above, long-lived assets include “Property, plant and equipment, net” and “Other long-term assets” from the consolidated balance sheets, by the geographic location where the asset resides.

Historical Timeline

Fiscal YearFiled
2025Mar 16, 2026Showing above
2024Mar 17, 2025

About Segments Disclosures

Segment disclosures break a company into its reportable operating units, revealing revenue, profit, and asset allocation that consolidated financial statements obscure. Under ASC 280, segments must match how the chief operating decision maker views the business, providing a window into internal management structure and resource allocation priorities.

Key signals: compare segment margins to identify which units drive profitability and which destroy value. Watch for changes in the number of reportable segments — segment aggregation or disaggregation often coincides with strategic shifts or attempts to obscure declining performance. Intersegment elimination patterns reveal internal pricing practices. The reconciliation between segment totals and consolidated figures exposes corporate overhead allocation and unallocated items. Geographic revenue concentration highlights regulatory and currency exposure. Compare segment-level capital expenditure against segment revenue to assess where management is investing for future growth versus harvesting existing assets.