We are a life science REIT focused on developing, redeveloping, and operating properties that provide space for lease to
tenants primarily in the life science industry. Our properties are leased predominantly through triple-net lease agreements and share
key characteristics, including generic and reusable improvements, consistent lease structures, and business strategy. All properties are
located within North America, predominantly in the U.S., and operate within a comparable regulatory environment.
Operating segments
Our Chief Operating Decision Maker (“CODM”), represented by our Executive Chairman and our Chief Executive Officer,
evaluates operating results at the geographic market level to assess performance and allocate resources. Our operating segments align
with our markets, including Greater Boston, the San Francisco Bay Area, San Diego, and Seattle, among others. Regular market
performance updates are provided directly to the CODM. These updates include each market’s net operating income (“NOI”), which
serves as the profit or loss measure used by the CODM for performance assessment and resource allocation. NOI provides useful
information regarding performance of each market as it reflects income and expenses incurred in connection with real estate operations
in each market. This metric enables the CODM to evaluate the profitability and performance of each market on a consistent and
comparable basis, supporting decisions on capital resource allocation, including in connection with development, redevelopment,
acquisition, and disposition activities in each market.
Evaluation of economic similarity and aggregation of operating segments
In accordance with the segment reporting accounting standard, we evaluate the economic similarity of our operating
segments. Seven of our nine operating segments exhibit consistent long-term economic characteristics, including similar historical long-
term NOI margins, which are also expected to remain similar in the future. Additionally, these markets share similar operational
characteristics, including nature of services provided (i.e., leasing, operating, developing, and redeveloping life science properties),
tenant base (i.e., a variety of tenants involved in the life science industry), methods of operation (i.e., consistent lease structures,
property management practices, and business strategies), nature of the regulatory environment (consistent across North America,
where all our operating segments are located). Based on shared economic characteristics, we have aggregated our seven operating
segments into one reportable segment for segment reporting purposes. Two of our operating segments, specifically our New York City
and Canada markets, do not meet the aggregation criteria and individually do not meet the quantitative thresholds to qualify as
reportable segments. Therefore, these operating segments are included in the “all other” category in the tables below.
The following table presents the reportable segment profit or loss measure, NOI, for the years ended December 31, 2025,
2024, and 2023 (in thousands).
Year Ended December 31,
2025
2024
2023
Reportable segment revenues:
Revenues from external customers
$2,798,270
$2,897,524
$2,685,027
Other income
37,012
30,028
21,408
Reportable segment total revenues
2,835,282
2,927,552
2,706,435
Reportable segment total rental operating expenses
(868,831)
(831,258)
(763,700)
Reportable segment net operating income (reportable segment profit or loss)
$1,966,451
$2,096,294
$1,942,735
Significant expenses included in the reportable segment profit or loss measure (i.e., NOI) are represented by the reportable
segment total rental operating expenses and are disclosed in the table above. These expenses primarily include property taxes, utilities,
repairs and maintenance, engineering, janitorial, and other costs.
Presented below are reconciliations of the reportable segment total revenues to the consolidated revenues, the reportable
segment total rental operating expenses to consolidated rental operations, the reportable segment net operating income to the
consolidated net income, and the reportable segment investments in real estate assets to the consolidated investments in real estate
assets (in thousands):
Year Ended December 31,
2025
2024
2023
Reconciliation of reportable segment revenues to consolidated total revenues:
Reportable segment total revenues
$2,835,282
$2,927,552
$2,706,435
All other revenues
191,274
188,842
179,264
Consolidated total revenues
$3,026,556
$3,116,394
$2,885,699
Reconciliation of reportable segment total rental operating expenses to
consolidated rental operations:
Reportable segment total rental operating expenses
$(868,831)
$(831,258)
$(763,700)
All other rental operating expenses
(53,774)
(78,007)
(95,480)
Consolidated rental operations
$(922,605)
$(909,265)
$(859,180)
Reconciliation of reportable segment net operating income to consolidated net
(loss) income:
Reportable segment net operating income (reportable segment profit or loss)
$1,966,451
$2,096,294
$1,942,735
All other revenues
191,274
188,842
179,264
All other rental operating expenses
(53,774)
(78,007)
(95,480)
Other items not allocated to segments:
General and administrative
(117,047)
(168,359)
(199,354)
Interest expense
(226,698)
(185,838)
(74,204)
Depreciation and amortization
(1,350,478)
(1,202,380)
(1,093,473)
Impairment of real estate
(2,202,818)
(223,068)
(461,114)
Loss on early extinguishment of debt
(107)
Equity in (losses) earnings of unconsolidated real estate joint ventures
(9,631)
7,059
980
Investment loss
(56,343)
(53,122)
(195,397)
Gain on sale of real estate
642,445
129,312
277,037
Consolidated net (loss) income
$(1,216,726)
$510,733
$280,994
As of December 31,
2025
2024
Reconciliation of reportable segment assets to consolidated investments in real estate assets
Reportable segment investments in real estate
$27,510,082
$30,393,144
All other investments in real estate
1,179,914
1,716,895
Consolidated investments in real estate
$28,689,996
$32,110,039

Historical Timeline

Fiscal YearFiled
2025Jan 26, 2026Showing above
2024Jan 27, 2025

About Segments Disclosures

Segment disclosures break a company into its reportable operating units, revealing revenue, profit, and asset allocation that consolidated financial statements obscure. Under ASC 280, segments must match how the chief operating decision maker views the business, providing a window into internal management structure and resource allocation priorities.

Key signals: compare segment margins to identify which units drive profitability and which destroy value. Watch for changes in the number of reportable segments — segment aggregation or disaggregation often coincides with strategic shifts or attempts to obscure declining performance. Intersegment elimination patterns reveal internal pricing practices. The reconciliation between segment totals and consolidated figures exposes corporate overhead allocation and unallocated items. Geographic revenue concentration highlights regulatory and currency exposure. Compare segment-level capital expenditure against segment revenue to assess where management is investing for future growth versus harvesting existing assets.