15. Segment Information

The Company operates as one operating segment, focused on discovering, developing and commercializing antiviral therapeutics. The determination of a single business segment is consistent with the consolidated financial information regularly provided to the Company’s CODM. As CODM, the Company’s chief executive officer, uses consolidated, single-segment financial information for purposes of evaluating performance, making operating decisions, allocating resources, and planning and forecasting for future periods.

The CODM assesses performance and decides how to allocate resources based on consolidated net loss. This measure is used to monitor budget versus actual results to evaluate the performance of the segment.

The CODM reviews cash, cash equivalents and marketable securities as a measure of segment assets. As of December 31, 2025 and 2024, the Company’s cash, cash equivalents and marketable securities were $301,830 and $454,721, respectively.

The following table illustrates information about significant segment expenses and segment operating loss for the years ended December 31, 2025 and 2024:

 

Year Ended December 31,

 

 

 

2025

 

 

2024

 

Research and development expense (1)

 

 

 

 

 

 

     HCV external costs (2)

 

$

109,574

 

 

$

34,106

 

     COVID-19 external costs (2)

 

 

1,490

 

 

 

60,734

 

Early stage discovery external costs (2)

 

 

3,800

 

 

 

943

 

     Compensation and related expenses

 

 

18,753

 

 

 

20,448

 

     Consulting and professional fees

 

 

2,183

 

 

 

1,959

 

     Other research and development expenses

 

 

1,778

 

 

 

1,839

 

Total research and development expense

 

 

137,578

 

 

 

120,029

 

General and administrative (3)

 

 

 

 

 

 

     Compensation and related expenses

 

 

9,094

 

 

 

9,279

 

     Consulting and professional fees

 

 

12,004

 

 

 

10,031

 

     Other general and administrative

 

 

1,491

 

 

 

1,844

 

Total general and administrative

 

 

22,589

 

 

 

21,154

 

Stock based compensation

 

 

20,720

 

 

 

51,767

 

Other segment items (4)

 

 

(22,538

)

 

 

(24,564

)

Net loss

 

$

(158,349

)

 

$

(168,386

)

 

 

 

 

 

 

 

(1) Research and development expense for the years ended December 31, 2025 and 2024 excludes stock based compensation of $10,446 and $24,072, respectively.

(2) External costs consist primarily of discovery, preclinical, clinical and manufacturing related activities.

(3) General and administrative expense for the years ended December 31, 2025 and 2024 excludes stock based compensation of $10,274 and $27,695, respectively.

(4) Other segment items include Interest income and other, net and income tax benefit (expense).

Historical Timeline

Fiscal YearFiled
2025Mar 5, 2026Showing above
2024Mar 6, 2025

About Segments Disclosures

Segment disclosures break a company into its reportable operating units, revealing revenue, profit, and asset allocation that consolidated financial statements obscure. Under ASC 280, segments must match how the chief operating decision maker views the business, providing a window into internal management structure and resource allocation priorities.

Key signals: compare segment margins to identify which units drive profitability and which destroy value. Watch for changes in the number of reportable segments — segment aggregation or disaggregation often coincides with strategic shifts or attempts to obscure declining performance. Intersegment elimination patterns reveal internal pricing practices. The reconciliation between segment totals and consolidated figures exposes corporate overhead allocation and unallocated items. Geographic revenue concentration highlights regulatory and currency exposure. Compare segment-level capital expenditure against segment revenue to assess where management is investing for future growth versus harvesting existing assets.