13. Segment Information

Operating segments are identified as components of an enterprise about which separate discrete financial information is available for evaluation by the chief operating decision-maker in making decisions regarding resource allocation and assessing performance. The Company is a clinical-stage biopharmaceutical company and has not generated any product revenue from its CAB antibody-based products. The Company’s operations are organized and reported as a single reportable segment, which includes all activities related to the discovery, development, and commercialization of its CAB products. The Company’s CODM, its chief executive officer, reviews operating results on an aggregate basis and manages the operations as a single operating segment. The measure of segment assets is reported on the consolidated balance sheets as total assets. The CODM evaluates performance and allocates resources based on consolidated net income or loss that also is reported on the consolidated statements of operations and comprehensive loss as net loss, and cash used in operations.

The following table provides R&D expenses by program with a reconciliation to net loss for the periods indicated, which are regularly reviewed by the CODM:

 

Years Ended December 31,

 

 

2025

 

 

2024

 

 

(in thousands)

 

Collaboration and other revenue

$

2,000

 

 

$

11,000

 

Program expenses:

 

 

 

 

 

Mecbotamab vedotin, BA3011 (CAB AXL-ADC)

 

7,848

 

 

 

12,934

 

Ozuriftamab vedotin, BA3021 (CAB ROR2-ADC)

 

5,446

 

 

 

8,962

 

Evalstotug, BA3071 (CAB CTLA-4)

 

5,026

 

 

 

9,103

 

BA3182 (CAB EpCAM x CAB CD3)

 

7,869

 

 

 

5,111

 

Other CAB Programs

 

3,768

 

 

 

6,912

 

Total program expenses

 

29,957

 

 

 

43,022

 

Personnel and related

 

8,180

 

 

 

12,082

 

Equity-based compensation

 

2,199

 

 

 

4,238

 

Facilities and other

 

3,237

 

 

 

3,753

 

Total research and development expenses

 

43,573

 

 

 

63,095

 

General and administrative expenses

 

 

 

 

 

Personnel and related

 

5,286

 

 

 

7,213

 

Equity-based compensation

 

3,235

 

 

 

4,683

 

Facilities and other

 

9,211

 

 

 

9,952

 

Total general and administrative expenses

 

17,732

 

 

 

21,848

 

Interest and other income (expense)

 

(302

)

 

 

4,167

 

Net loss and comprehensive loss

$

(59,607

)

 

$

(69,776

)

Historical Timeline

Fiscal YearFiled
2025Mar 31, 2026Showing above
2024Mar 28, 2025

About Segments Disclosures

Segment disclosures break a company into its reportable operating units, revealing revenue, profit, and asset allocation that consolidated financial statements obscure. Under ASC 280, segments must match how the chief operating decision maker views the business, providing a window into internal management structure and resource allocation priorities.

Key signals: compare segment margins to identify which units drive profitability and which destroy value. Watch for changes in the number of reportable segments — segment aggregation or disaggregation often coincides with strategic shifts or attempts to obscure declining performance. Intersegment elimination patterns reveal internal pricing practices. The reconciliation between segment totals and consolidated figures exposes corporate overhead allocation and unallocated items. Geographic revenue concentration highlights regulatory and currency exposure. Compare segment-level capital expenditure against segment revenue to assess where management is investing for future growth versus harvesting existing assets.