14.

Segment reporting and geographic information

 

For the years ended December 31, 2024 and 2025, the Company operated in two reportable segments: (i) Plinabulin pipeline and (ii) TPD platform.

 

On December 13, 2024, the Company’s Board of Directors discussed and approved a divestiture plan to sell and transfer about 90% to 100% of the Company’s interests in SEED to potential investors at a determined price. The TPD platform segment was comprised of SEED’s operations. As a result, for the years ended December 31, 2024 and 2025, the TPD platform segment qualified for discontinued operations reporting. See Note 3 – Discontinued operations.

 

The Company presents segment information after elimination of inter-company transactions. In general, revenues and operating expenses are directly attributable, or are allocated, to each segment. The Company allocates operating expenses that are not directly attributable to a specific segment, such as those that support infrastructure across different segments, to different segments mainly on the basis of usage, headcount, depending on the nature of the relevant operating expenses.

 

The Company’s Chief Executive Officer, as the CODM, uses segment net loss to allocate resources for each segment and to assess the performance of each segment, primarily by monitoring actual results versus approved budgets. Significant segment expenses are presented in the table below. Other segment items include interest income, other income, net, and income tax expenses. The CODM does not evaluate the performance of segments using asset or liability information.

 

   

For the year ended December 31,

 
   

2024

   

2025

 
   

$

   

$

 
                 

Clinical and pre-clinical expenses

    462       1,630  

Patent expenses

    928       792  

Personnel costs

    4,642       3,196  

Professional services

    1,442       1,958  

Other operational expenses

    1,280       1,369  

Other segment items

    111       (230 )

Segment net loss

    8,865       8,715  

Reconciliation of net loss:

               

Net loss from discontinued operations

    7,828       5,502  

Consolidated net loss

    16,693       14,217  

 

The Company’s long-lived assets of continuing operations by geographic area are presented as follows:

 

   

December 31,

 
   

2024

   

2025

 
   

$

   

$

 

Property and equipment, net:

               
                 

PRC

    34       11  

U.S.

    205       155  
                 

Total

    239       166  

 

Historical Timeline

Fiscal YearFiled
2025Mar 25, 2026Showing above
2024Mar 27, 2025

About Segments Disclosures

Segment disclosures break a company into its reportable operating units, revealing revenue, profit, and asset allocation that consolidated financial statements obscure. Under ASC 280, segments must match how the chief operating decision maker views the business, providing a window into internal management structure and resource allocation priorities.

Key signals: compare segment margins to identify which units drive profitability and which destroy value. Watch for changes in the number of reportable segments — segment aggregation or disaggregation often coincides with strategic shifts or attempts to obscure declining performance. Intersegment elimination patterns reveal internal pricing practices. The reconciliation between segment totals and consolidated figures exposes corporate overhead allocation and unallocated items. Geographic revenue concentration highlights regulatory and currency exposure. Compare segment-level capital expenditure against segment revenue to assess where management is investing for future growth versus harvesting existing assets.