8.         Income Taxes

 

At December 31, 2025, we have a consolidated federal net operating loss (“NOL”) carryforward of approximately $135.4 million available to offset against future taxable income of which approximately $25.7 million expires in varying amounts in 2026 through 2037. Additionally, we have approximately $6.7 million in research and development (“R&D”) tax credits that expire in 2026 through 2045 unless utilized earlier. No income taxes have been paid to date. Section 382 of the Internal Revenue Code contains provisions that may limit our utilization of our NOL and R&D tax credit carryforwards in any given year as a result of significant changes in ownership interests that have occurred in past periods or may occur in future periods.

 

Deferred income taxes reflect the net effect of temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and the amounts used for income tax purposes. We have established a full valuation allowance equal to the amount of our net deferred tax assets due to uncertainties with respect to our ability to generate sufficient taxable income to realize these assets in the future. The table below presents significant components of our deferred tax assets and liabilities at December 31, 2025 and 2024.

 

   

2025

   

2024

 

Deferred tax assets:

               

Net operating loss carryforward

  $ 35,197,253     $ 30,374,640  

Research and development tax credit carryforward

    6,709,611       5,506,154  

Stock-based compensation expense

    965,107       676,250  

Accrued expenses

    47,212       256,540  

Total deferred tax assets

    42,919,183       36,813,584  

Deferred tax liabilities

               

Depreciation

    18,298       29,812  

Net deferred tax assets

    42,900,885       36,783,772  

Valuation allowance

    (42,900,885 )     (36,783,772 )

Net deferred tax asset after reduction for valuation allowance

  $ 0     $ 0  

 

A reconciliation of the U.S. federal income tax rate to the Company’s effective tax rate is as follows:

 

   

2025

   

2024

 

U.S. federal statutory rate applied to pretax loss

    21.0 %     21.0 %

State income tax (benefit)

    4.0       4.0  

Permanent differences

    (0.0 )     (0.0 )

NOL carryforward expiration

    (2.5 )     (4.1 )

R&D tax credits, net of expiration

    5.7       6.5  

Change in valuation allowance and other adjustments

    (28.2 )     (27.4 )

Effective tax rate

    0.0 %     0.0 %

  

Historical Timeline

Fiscal YearFiled
2025Apr 15, 2026Showing above
2024Mar 27, 2025
2023Feb 29, 2024
2022Mar 23, 2023
2021Mar 9, 2022
2020Mar 23, 2021
2019Mar 24, 2020
2018Mar 26, 2019
2017Mar 23, 2018
2016Mar 24, 2017
2015Mar 16, 2016

About Income Taxes Disclosures

The income tax disclosure reveals how much a company actually pays in taxes versus what the statutory rate would predict. Analysts focus on the effective tax rate (ETR) reconciliation, which breaks down every item driving the gap between the 21% federal rate and the company's reported ETR — including R&D credits, foreign rate differentials, and state taxes. Deferred tax assets (DTAs) and their valuation allowances signal management's confidence in future profitability: a rising allowance suggests the company doubts it can use accumulated tax benefits. Uncertain tax benefit (UTB) reserves quantify exposure to IRS challenges on aggressive positions.

Key signals to watch: sudden ETR drops without clear operational reasons, large increases in valuation allowances, growing UTB balances, and significant unremitted foreign earnings. Post-TCJA, pay attention to GILTI and BEAT provisions that affect multinational tax structures. Compare the cash taxes paid (from the cash flow statement) against the income tax provision to gauge earnings quality.