17. Segment Information

The Company operates and manages its business as a single operating and reportable segment for the purpose of assessing performance and making operating decisions. The Company’s chief executive officer, who is the CODM, reviews the Company’s financial information on an aggregated basis for purposes of evaluating financial performance and allocating resources. The CODM assesses operating performance as compared to planned activities for the operating segment and decides how to allocate resources based on net loss that also is reported on the consolidated statement of operations and comprehensive loss. The Company derives license revenue primarily in the United States from research

and development collaborations and manages the business activities on a consolidated basis. In addition, all segment assets are held in the United States.

In addition, the CODM is regularly provided the following significant segment financial information to assist in segment performance evaluation, resource allocation, and decision-making (in thousands):

 

 

Year Ended December 31,

 

 

2025

 

 

2024

 

License Revenue

 

$

800

 

 

$

3,500

 

Research and Development

 

 

 

 

 

 

Clinical research and outside services

 

$

13,752

 

 

$

12,666

 

Compensation and related

 

 

4,403

 

 

 

4,001

 

Other research and development expenses(a)

 

 

 

 

 

15,442

 

Stock-based compensation expense

 

 

10,370

 

 

 

 

Total research and development expense

 

$

28,525

 

 

$

32,109

 

General and Administrative

 

 

 

 

 

 

Compensation and related

 

 

5,182

 

 

 

2,645

 

Consulting and professional services

 

 

6,335

 

 

 

3,152

 

Other general and administrative expenses(b)

 

 

4,188

 

 

 

2,594

 

Stock-based compensation expense

 

 

5,021

 

 

 

 

Total general and administrative expense

 

$

20,726

 

 

$

8,391

 

 

(a)
Other research and development expenses include non-cash research and development expense for issuance of ordinary shares related to the Hutchmed Agreement of $14.0 million for the year ended December 31, 2024, and certain departmental expenses.
(b)
Other general and administrative expenses include depreciation expense, amortization expense, and certain departmental expenses.

Historical Timeline

Fiscal YearFiled
2025Mar 10, 2026Showing above
2024Mar 6, 2025

About Segments Disclosures

Segment disclosures break a company into its reportable operating units, revealing revenue, profit, and asset allocation that consolidated financial statements obscure. Under ASC 280, segments must match how the chief operating decision maker views the business, providing a window into internal management structure and resource allocation priorities.

Key signals: compare segment margins to identify which units drive profitability and which destroy value. Watch for changes in the number of reportable segments — segment aggregation or disaggregation often coincides with strategic shifts or attempts to obscure declining performance. Intersegment elimination patterns reveal internal pricing practices. The reconciliation between segment totals and consolidated figures exposes corporate overhead allocation and unallocated items. Geographic revenue concentration highlights regulatory and currency exposure. Compare segment-level capital expenditure against segment revenue to assess where management is investing for future growth versus harvesting existing assets.