iSpecimen Inc. Income Taxes Disclosure
12. INCOME TAXES
There was provision for income taxes for the years ended December 31, 2025 and 2024 due to the Company’s operating losses and a full valuation allowance on deferred tax assets.
The Company completed research and development studies covering all tax years currently under the applicable statute of limitations.
Significant components of the Company’s deferred tax assets and liabilities as of December 31 are as follows:
| 2025 | 2024 | |||||||
| Deferred tax assets: | ||||||||
| Operating loss carryforwards | $ | 17,786,885 | $ | 15,387,300 | ||||
| Research and development tax credit | 2,220,972 | 2,155,100 | ||||||
| Other | 892,216 | 868,700 | ||||||
| Total deferred tax assets | 20,900,073 | 18,411,100 | ||||||
| Deferred tax liability: | ||||||||
| Other | (73,500 | ) | (80,500 | ) | ||||
| Intangibles | (59,400 | ) | (124,800 | ) | ||||
| Total deferred tax liabilities | (132,900 | ) | (205,300 | ) | ||||
| Net deferred tax assets before valuation allowance | 20,767,173 | 18,205,800 | ||||||
| Valuation allowance | (20,767,173 | ) | (18,205,800 | ) | ||||
| Net deferred tax asset | $ | $ | ||||||
The Company has provided a valuation allowance against the deferred tax assets as it has incurred significant losses since its inception. Management currently believes that it is more likely than not that the deferred tax assets will not be realized in the future. The change in the valuation allowance during 2024 was an increase of $3,044,600.
As of December 31, 2025 and December 31, 2024, the Company had federal net operating loss carryforwards of approximately $72,600,000 and $62,300,000, respectively, of which approximately $13,000,000 expires at various periods through 2037 and approximately $59,600,000 can be carried forward indefinitely. As of December 31, 2025 and December 31, 2024, the Company had state net operating loss carryforwards of approximately $39,767,000 and $35,600,000, respectively, that expire at various periods through 2045, respectively. At December 31, 2025 and December 31, 2024, the Company had federal and state tax credits of approximately $2,221,000 and $2,031,000, respectively, available for future periods that expire at various periods through 2045. The Company has recorded a full valuation allowance against net deferred income tax assets due to a history of losses generated since inception.
Due to changes in ownership provisions of the Internal Revenue Code, the availability of the Company’s NOL carryforwards may be subject to annual limitations under Section 382 of the Internal Revenue Code against taxable income in the future period, which could substantially limit the eventual utilization of such carryforwards.
The Company applies the standards on uncertainty in income taxes. The Company did not have any significant unrecognized tax benefits during the year ended December 31, 2025. The Company’s U.S. federal operating losses have occurred since its inception and as such, tax years subject to potential tax examination could apply from that date because the utilization of net operating losses from prior years opens the relevant year to audit by the IRS and/or state taxing authorities.
The Company’s income tax provision was computed using the federal statutory rate and average state statutory rates, net of related federal benefit. The following represents a reconciliation of the statutory income tax rates to the effective rates at December 31:
| 2025 | 2024 | |||||||
| Reconciliation to statutory rates | ||||||||
| Expected federal income taxes benefit at statutory rates | (21.0 | )% | (21.0 | )% | ||||
| Expected state tax benefit at statutory rates, net of federal benefit | (6.4 | ) | (6.4 | ) | ||||
| Change in valuation allowance | 27.4 | 27.4 | ||||||
| Income tax expense (benefit) | % | % | ||||||
Historical Timeline
| Fiscal Year | Filed | |
|---|---|---|
| 2025 | Apr 1, 2026 | Showing above |
| 2024 | Apr 14, 2025 | |
| 2023 | Mar 13, 2024 | |
| 2022 | Mar 21, 2023 | |
| 2021 | Mar 22, 2022 | |
About Income Taxes Disclosures
The income tax disclosure reveals how much a company actually pays in taxes versus what the statutory rate would predict. Analysts focus on the effective tax rate (ETR) reconciliation, which breaks down every item driving the gap between the 21% federal rate and the company's reported ETR — including R&D credits, foreign rate differentials, and state taxes. Deferred tax assets (DTAs) and their valuation allowances signal management's confidence in future profitability: a rising allowance suggests the company doubts it can use accumulated tax benefits. Uncertain tax benefit (UTB) reserves quantify exposure to IRS challenges on aggressive positions.
Key signals to watch: sudden ETR drops without clear operational reasons, large increases in valuation allowances, growing UTB balances, and significant unremitted foreign earnings. Post-TCJA, pay attention to GILTI and BEAT provisions that affect multinational tax structures. Compare the cash taxes paid (from the cash flow statement) against the income tax provision to gauge earnings quality.