16. Segment Reporting

The Company operates as a single reportable and operating segment dedicated to the research and development, commercialization, and sale of mAbs in the U.S to deliver protection from serious viral infectious diseases.

The determination of a single reportable segment is consistent with the consolidated financial information regularly reviewed by the Chief Operating Decision Maker (the “CODM”) in assessing performance and deciding how to allocate resources on a consolidated basis. The CODM is the Principal Executive Officer, who also serves as the Chief Financial Officer.

The CODM assesses performance and allocates resources based on the Company’s net loss reported on the consolidated statements of operations and comprehensive loss. The CODM’s area of focus is period over period fluxes and budget-to-actual variances when assessing performance and deciding how to allocate resources. The Company’s reportable segment derives its revenues from sales of its product, PEMGARDA. No asset information has been provided for the reportable segment as the CODM does not regularly review asset information by reportable segment.

The following table presents information about reported segment revenues, and significant segment expenses as provided to the CODM (in thousands). Certain prior period segment expense amounts have been recast to reflect the current year presentation.

 

 

 

Year Ended December 31,

 

 

Year Ended December 31,

 

 

 

2025

 

 

2024

 

Revenue:

 

 

 

 

 

 

Product revenue, net

 

$

53,426

 

 

$

25,384

 

Total revenue

 

 

53,426

 

 

 

25,384

 

Operating costs and expenses:

 

 

 

 

 

 

Cost of product revenue

 

 

3,747

 

 

 

1,618

 

Research and development expense

 

 

 

 

 

 

Direct, external research and development expenses by program:

 

 

 

 

 

 

Pemivibart(1)

 

 

3,140

 

 

 

31,757

 

VYD2311(2)

 

 

4,597

 

 

 

67,505

 

VBY329(3)

 

 

615

 

 

 

 

Early-stage programs

 

 

428

 

 

 

974

 

   Total direct, external research and development expenses by program

 

 

8,780

 

 

 

100,236

 

Personnel expense (research and development)

 

 

11,746

 

 

 

16,294

 

Stock-based compensation (research and development)

 

 

3,037

 

 

 

4,980

 

Other research and development expenses

 

 

14,745

 

 

 

15,744

 

Total research and development expenses

 

 

38,308

 

 

 

137,254

 

Selling, general and administrative expense

 

 

 

 

 

 

Sales and Marketing costs

 

 

13,786

 

 

 

15,990

 

Personnel expense (selling, general and administrative)

 

 

22,651

 

 

 

15,101

 

Stock-based compensation (selling, general and administrative)

 

 

8,606

 

 

 

14,808

 

Other selling, general and administrative expenses

 

 

21,888

 

 

 

17,489

 

Total selling, general and administrative expenses

 

 

66,931

 

 

 

63,388

 

Total operating costs and expenses

 

 

108,986

 

 

 

202,260

 

Loss from operations

 

 

(55,560

)

 

 

(176,876

)

Other income:

 

 

 

 

 

 

Other income, net(4)

 

 

3,071

 

 

 

6,951

 

Total other income, net

 

 

3,071

 

 

 

6,951

 

Net loss

 

$

(52,489

)

 

$

(169,925

)

 

(1)
In March 2023, the Company announced the nomination of VYD222 (pemivibart) as a novel mAb therapeutic option for COVID-19.
(2)
In March 2024, the Company announced the nomination of VYD2311 as a novel mAb therapeutic option for COVID-19.
(3)
In November 2025, the Company announced the nomination of VBY329 as an RSV mAb candidate for preclinical development.
(4)
Includes interest income of $3,107 and $7,216 for the years ended December 31, 2025 and 2024, respectively.

Historical Timeline

Fiscal YearFiled
2025Mar 5, 2026Showing above
2024Mar 20, 2025

About Segments Disclosures

Segment disclosures break a company into its reportable operating units, revealing revenue, profit, and asset allocation that consolidated financial statements obscure. Under ASC 280, segments must match how the chief operating decision maker views the business, providing a window into internal management structure and resource allocation priorities.

Key signals: compare segment margins to identify which units drive profitability and which destroy value. Watch for changes in the number of reportable segments — segment aggregation or disaggregation often coincides with strategic shifts or attempts to obscure declining performance. Intersegment elimination patterns reveal internal pricing practices. The reconciliation between segment totals and consolidated figures exposes corporate overhead allocation and unallocated items. Geographic revenue concentration highlights regulatory and currency exposure. Compare segment-level capital expenditure against segment revenue to assess where management is investing for future growth versus harvesting existing assets.