Income Taxes
The components of loss from continuing operations before income taxes are presented below:
Year Ended December 31,
202520242023
United States$(250,719)$(85,879)$(93,522)
Foreign80 (42,149)(2,840)
Total$(250,639)$(128,028)$(96,362)
The components of income tax expense (benefit) from continuing operations are presented below:
Year Ended December 31,
202520242023
Current tax expense
US federal— — — 
US state and local21 
Foreign— — — 
Total current tax expense 21 
Deferred tax (benefit)
US federal— (41)(247)
US state and local— (11)(80)
Foreign— (1,743)(152)
Total deferred tax (benefit)— (1,795)(479)
Total income tax expense (benefit)
US federal— (41)(247)
US state and local(9)(59)
Foreign— (1,743)(152)
Total income tax expense (benefit)$$(1,793)$(458)
There were no significant tax payments made to any jurisdiction, or state income tax expense incurred, during the periods presented above.
Income tax expense (benefit) for the years ended December 31, 2025, 2024, and 2023 differed from amounts computed by applying the applicable United States federal corporate income tax rate of 21% to loss before income taxes as a result of the following:
Year Ended December 31,
202520242023
AmountPercentAmountPercentAmountPercent
US federal statutory income tax rate(52,634)21.0 %(26,886)21.0 %(20,236)21.0 %
Domestic federal
Research and development tax credits(1,200)0.5 %(1,750)1.4 %(1,146)1.2 %
Nontaxable and nondeductible items
Stock based compensation— %313 (0.2)%3,417 (3.5)%
Change in fair value of warrants29,300 (11.7)%61 — %— — %
Other1,631 (0.7)%333 (0.3)%324 (0.3)%
Change in valuation allowance23,820 (9.5)%19,831 (15.5)%15,758 (16.4)%
Other(903)0.4 %(794)0.6 %867 (0.9)%
Domestic state and local income taxes, net of federal effect— %(7)— %(42)— %
Foreign
Belgium
Statutory income tax rate differential— %(1,081)0.8 %34 — %
Impairment of goodwill— — %551 (0.4)%— — %
Other— — %770 (0.6)%(414)0.4 %
Change in valuation allowance(20)— %6,866 (5.4)%895 (0.9)%
Other foreign jurisdictions— — %— — %85 (0.1)%
Total income tax expense (benefit)$— %$(1,793)1.4 %$(458)0.5 %
The tax effects of temporary differences that comprise the deferred tax assets and liabilities as of December 31, 2025, and 2024, are as follows:
20252024
Deferred tax assets
Equity securities and investments in affiliates517 472 
Property, plant and equipment302 237 
Intangible assets47,753 56,113 
Accrued liabilities2,789 2,478 
Lease liabilities1,220 1,383 
Stock-based compensation13,472 14,205 
Deferred revenue56 503 
Capitalized research and development cost21,224 29,796 
Research and development tax credits17,928 16,232 
Net operating, capital loss, and interest expense carryforwards285,791 283,926 
Total deferred tax assets391,052 405,345 
Less: Valuation allowance389,936 404,074 
Net deferred tax assets1,116 1,271 
Deferred tax liabilities
Right-of-use assets1,116 1,271 
Total deferred tax liabilities1,116 1,271 
Net deferred tax liabilities included in continuing operations$— $— 
Activity within the valuation allowance for deferred tax assets included in continuing operations during the years ended December 31, 2025, 2024, and 2023 was as follows:
202520242023
Valuation allowance at beginning of year$404,074 $424,432 $401,086 
Increase (decrease) in valuation allowance as a result of
Current year operations10,069 30,783 23,065 
Expired attributes
(26,394)(50,269)— 
Foreign currency translation adjustment2,187 (872)281 
Valuation allowance at end of year$389,936 $404,074 $424,432 
In assessing the realizability of deferred tax assets, management considers whether it is more likely than not that some portion or all of the deferred tax assets will not be realized. The ultimate realization of deferred tax assets is dependent upon the generation of future taxable income during the periods in which those temporary differences become deductible. Management considers the scheduled reversal of deferred tax liabilities, projected future taxable income and tax planning strategies in making this assessment. Due to the Company and its subsidiaries' histories of net losses incurred from inception, any corresponding net domestic and foreign deferred tax assets have been fully reserved as the Company and its subsidiaries cannot sufficiently be assured that these deferred tax assets will be realized.
The Company's past issuances of stock and mergers and acquisitions have resulted in ownership changes as defined in Section 382 of the Internal Revenue Code of 1986, as amended ("Section 382"). As a result, utilization of portions of the net operating losses may be subject to annual limitations. As of December 31, 2025, approximately $31,466 of the Company's domestic net operating losses were inherited via acquisition and are limited based on the value of the target at the time of the transaction.
As of December 31, 2025, the Company had net operating loss carryforwards of approximately $1,120,424 for United States federal income tax purposes available to offset future taxable income, including $911,880 generated after 2017, United States capital loss carryforwards of $1,372, and United States federal and state research and development tax credits of approximately $17,880, prior to consideration of annual limitations that may be imposed under Section 382 of the Internal Revenue Code of 1986, as amended, or ("Section 382"). Net operating loss carryforwards generated prior to 2018 will expire if unutilized from 2026 to 2037, and capital loss carryforwards will expire if unutilized from 2027 to 2029. As a result of our past stock issuances, as well as due to prior mergers and acquisitions, certain of our net operating losses have been subject to limitations pursuant to Section 382. Future changes in stock ownership may also trigger an ownership change and, consequently, a Section 382 limitation. As of December 31, 2025, our direct foreign subsidiaries included in continuing operations had foreign loss carryforwards of approximately $80,104, most of which do not expire.
The Company and its subsidiaries do not have material unrecognized tax benefits as of December 31, 2025. The Company's U.S. tax returns for the years 2006 and forward are subject to examination by federal or state tax authorities due to the carryforward of unutilized net operating and capital losses and research and development tax credits.

Historical Timeline

Fiscal YearFiled
2025Mar 25, 2026Showing above
2024Mar 19, 2025
2023Mar 19, 2024
2022Mar 6, 2023
2021Mar 1, 2022
2020Mar 1, 2021
2019Mar 2, 2020
2018Mar 1, 2019
2017Mar 1, 2018
2016Mar 1, 2017
2015Feb 29, 2016

About Income Taxes Disclosures

The income tax disclosure reveals how much a company actually pays in taxes versus what the statutory rate would predict. Analysts focus on the effective tax rate (ETR) reconciliation, which breaks down every item driving the gap between the 21% federal rate and the company's reported ETR — including R&D credits, foreign rate differentials, and state taxes. Deferred tax assets (DTAs) and their valuation allowances signal management's confidence in future profitability: a rising allowance suggests the company doubts it can use accumulated tax benefits. Uncertain tax benefit (UTB) reserves quantify exposure to IRS challenges on aggressive positions.

Key signals to watch: sudden ETR drops without clear operational reasons, large increases in valuation allowances, growing UTB balances, and significant unremitted foreign earnings. Post-TCJA, pay attention to GILTI and BEAT provisions that affect multinational tax structures. Compare the cash taxes paid (from the cash flow statement) against the income tax provision to gauge earnings quality.