12. Income Taxes 

 

Total loss before income taxes for the years ended December 31, 2025 and 2024 were $72.8 million and $53.6 million, respectively. All losses were domestic and there were no foreign losses. 

 

During the years ended December 31, 2025 and 2024, the Company did not recognize an income tax provision.

 

The provision for income taxes differs from the amount estimated by applying the statutory federal income tax rate to net loss before taxes as follows:

 

  

Year Ended December 31,

 
  

2025

  

2024

 

Tax at federal statutory rate

 $(15,284)  21.0% $(11,253)  21.0%

State income tax, net of federal tax benefit1

  21      (2,993)  5.6 

Research and development credits

  (1,028)  1.4   (901)  1.7 

Nontaxable or nondeductible items

                

Stock-based compensation

  1,043   (1.4)  561   (1.0)

Other

  533   (0.7)  26   (0.1)

Changes in unrecognized tax benefits

  494   (0.7)  3,444   (6.4)

Change in valuation allowance

  14,221   (19.6)  11,116   (20.8)

Effective Tax Rate

 $   % $   %

___________________

1  State taxes in California comprise the majority (greater than 50 percent) of the state and local income taxes, net of federal effect category for both 2024 and 2025.

 

Deferred income taxes reflect the impact of carryforwards and temporary differences between the amounts of assets and liabilities for financial reporting purposes and such amounts as measured by tax laws. The carryforwards and temporary differences, which give rise to a significant portion of the Company’s deferred tax assets and liabilities as of December 31, 2025 and 2024, are as follows (in thousands):

 

  

December 31,

 
  

2025

  

2024

 

Deferred tax assets

        

Accruals

 $503  $1,218 

Net operating loss carryforwards

  74,859   66,952 

Tax credit carryforwards

  12,008   10,838 

Stock-based compensation

  14,450   9,588 

R&D capitalization

  18,527   10,358 

Lease liability

  1,890   1,869 

Property and equipment

  43   35 

Intangible assets

  544   279 

Gross deferred tax assets

  122,824   101,137 

Valuation allowance

  (121,249)  (99,542)

Total deferred tax assets

  1,575   1,595 
         

Deferred tax liabilities

        

Right-of-use assets

  (1,575)  (1,595)

Total deferred tax liabilities

  (1,575)  (1,595)
         

Net deferred tax assets/(liabilities)

 $  $ 

 

The Company’s unrecognized tax benefits as of December 31, 2025 and 2024 were $18.5 million and $17.4 million, respectively. If recognized, none of the unrecognized tax benefits would impact income tax expense to the extent that the Company continues to maintain a full valuation allowance against its deferred tax assets.

 

A reconciliation of the beginning and ending amounts of unrecognized tax benefit is as follows (in thousands):

 

  

December 31,

 
  

2025

  

2024

 

Unrecognized tax benefits at beginning of year

 $17,376  $10,170 

Increases related to current year tax positions

  1,405   4,366 

Increases related to prior year tax positions

     2,993 

Decreases related to prior year tax positions

  (255)  (153)

Unrecognized tax benefits at end of year

 $18,526  $17,376 

 

The Company’s policy is to recognize interest and penalties related to income taxes as components of interest expense and other expense, respectively. The Company did not accrue interest and penalties related to unrecognized tax benefits as of December 31, 2025 and does not anticipate any significant change within twelve months of this reporting date.

 

The Company’s valuation allowance increased by $21.7 million in the year ended December 31, 2025 and increased by $11.7 million in the year ended December 31, 2024.

 

As of December 31, 2025, the Company had federal and state net operating loss (“NOL”) carryforwards of $575.0 million which begin to expire in 2034. Of the $281.9 million of federal NOLs, $256.3 million is carried forward indefinitely but is limited to 80% of the taxable income.

 

As of December 31, 2025, the Company had U.S. federal and California research and development (“R&D”) tax credits of approximately $10.5 million, and $10.6 million, respectively. The federal R&D credits begin to expire in 2035, while California credits do not expire.

 

The Company is subject to taxation in the United States for Federal and State. All jurisdictions and tax years currently remain open for IRS examination. As of December 31, 2025, the Company was not under examination by the Internal Revenue Service or any state tax jurisdiction.

 

Internal Revenue Code Section 382 ownership change generally occurs if one or more stockholders or groups of stockholders who own at least 5% of our stock increase their ownership by more than 50 percentage points over their lowest ownership percentage within a rolling three-year period. Similar rules may apply under state tax laws. We believe that we have had one or more ownership changes prior to 2018, but recently performed a Section 382 study to analyze fiscal years 2018 through 2024, and we do not believe that we have had any additional ownership changes over that period. Possible future changes in our stock ownership could result in limitations.

 

On July 4, 2025, H.R. 1, a U.S. budget reconciliation bill, was signed into law. The Company has assessed the provisions of the new legislation and has integrated the resulting impacts into its effective income tax rate. Management has concluded that the bill does not have an impact on the Company's consolidated financial statements for the current period. 

Historical Timeline

Fiscal YearFiled
2025Feb 19, 2026Showing above
2024Mar 31, 2025
2023Mar 28, 2024
2021Mar 31, 2022
2020Mar 12, 2021
2019Mar 16, 2020

About Income Taxes Disclosures

The income tax disclosure reveals how much a company actually pays in taxes versus what the statutory rate would predict. Analysts focus on the effective tax rate (ETR) reconciliation, which breaks down every item driving the gap between the 21% federal rate and the company's reported ETR — including R&D credits, foreign rate differentials, and state taxes. Deferred tax assets (DTAs) and their valuation allowances signal management's confidence in future profitability: a rising allowance suggests the company doubts it can use accumulated tax benefits. Uncertain tax benefit (UTB) reserves quantify exposure to IRS challenges on aggressive positions.

Key signals to watch: sudden ETR drops without clear operational reasons, large increases in valuation allowances, growing UTB balances, and significant unremitted foreign earnings. Post-TCJA, pay attention to GILTI and BEAT provisions that affect multinational tax structures. Compare the cash taxes paid (from the cash flow statement) against the income tax provision to gauge earnings quality.