Segment and Geographic Area Information
The Company discloses information about its operating segments based on the way that management organizes the segments within the Company for making operating decisions and assessing financial performance. The CODM of the Company is the Chief Executive Officer (“CEO”). The CEO evaluates the performance of its operating segments based on revenue and operating income as adjusted for certain items. Intersegment revenue and transfers are not significant. The accounting policies of the operating segments are the same as those described in Note 1.
Effective at the beginning of fiscal year 2025, the Company implemented changes to its operating model. The majority of the Company’s Applied Genomics business, previously reported as part of the Diagnostics segment, has been integrated into a newly formed Life Sciences Solutions business, encompassing all Life Sciences reagents and consumables, instruments and services, as well as technology and licensing, which is reported as part of the Life Sciences segment. Beginning in fiscal year 2025, the Life Sciences segment consists of Life Sciences Solutions and Software, while the Diagnostics segment consists of Immunodiagnostics and Reproductive Health.
The effect of the change is not significant. Prior period financial information has been reclassified to reflect this new segment composition for consistent comparison.
The Company has included the expenses for its corporate headquarters, such as legal, tax, audit, human resources, information technology, and other management and compliance costs, as well as the activity related to the mark-to-market adjustment on postretirement benefit plans, as “Corporate” below. The Company has a process to allocate and recharge
expenses to the reportable segments when these costs are administered or paid by the corporate headquarters based on the extent to which the segment benefited from the expenses. These amounts have been calculated in a consistent manner and are included in the Company’s calculations of segment results to internally plan and assess the performance of each segment for all purposes, including determining the compensation of the business leaders for each of the Company’s operating segments.
The primary financial measure by which the Company evaluates the performance of its segments is adjusted operating income, which consists of operating income plus amortization of intangible assets, adjustments to operations arising from purchase accounting (primarily adjustments to the fair value of acquired inventory that are subsequently recognized), acquisition and divestiture-related costs, and other costs that are not expected to recur or are of a non-cash nature, primarily including restructuring actions, significant litigation matters and transformation costs. The CODM does not evaluate operating segments using discrete asset information and there are no segment assets reported to the CODM. Accordingly, no segment assets have been reported.
Revenue and operating income, including significant segment expenses, by reportable segment are shown in the table below for the fiscal years ended: 
December 28, 2025December 29, 2024December 31, 2023
Life
 Sciences
DiagnosticsTotalLife SciencesDiagnosticsTotalLife SciencesDiagnosticsTotal
(In thousands)
Segment revenue$1,431,104 $1,424,947 $2,856,051 $1,398,601 $1,356,425 $2,755,026 $1,458,192 $1,292,379 $2,750,571 
Segment cost of revenue516,297 633,769 488,188 576,162 510,445 548,612 
Segment selling, general and administrative expenses344,516 343,430 338,755 336,325 328,068 341,155 
Segment research and development expenses112,029 103,582 104,382 90,000 107,429 104,585 
Segment operating income$458,262 $344,166 802,428 $467,276 $353,938 821,214 $512,250 $298,027 810,277 
Corporate expenses(28,944)(41,754)(40,417)
Amortization of intangible assets(335,586)(359,376)(365,113)
Purchase accounting adjustments(1,248)79 (5,956)
Acquisition and divestiture-related costs(3,783)(25,379)(69,159)
Transformation costs(9,280)— — 
Asset impairment— (22,814)— 
Significant litigation matters and settlements(12,228)(7,775)(12)
Significant environmental matters1,208 — (2,457)
Restructuring and other, net(55,932)(17,454)(26,601)
Interest and other expense, net(88,358)(30,615)(117,586)
Income from continuing operations before income taxes$268,277 $316,126 $182,976 
Depreciation expense included in the Company’s reportable segment operating income and corporate expenses is as follows:
 December 28,
2025
December 29,
2024
December 31,
2023
 (In thousands)
Life Sciences$33,485 $30,128 $30,110 
Diagnostics33,403 36,074 33,994 
Corporate2,867 2,271 2,551 
Total depreciation expense$69,755 $68,473 $66,655 
The following geographic area information for continuing operations includes revenue based on location of external customers for the three fiscal years ended December 28, 2025 and net long-lived assets based on physical location as of December 28, 2025 and December 29, 2024:
 Revenue
 December 28,
2025
December 29,
2024
December 31,
2023
 (In thousands)
U.S.$1,126,274 $1,097,856 $1,117,654 
International:
China425,060 450,007 454,426 
Germany177,664 162,575 193,170 
United Kingdom126,849 112,883 125,419 
Other international1,000,204 931,705 859,902 
Total international1,729,777 1,657,170 1,632,917 
Total revenue$2,856,051 $2,755,026 $2,750,571 
 
 
Net Long-Lived Assets (a)
 December 28,
2025
December 29,
2024
 (In thousands)
U.S.$341,172 $348,868 
International:
Germany130,645 134,713 
United Kingdom40,839 35,097 
China34,894 49,207 
Other international201,481 177,995 
Total international407,859 397,012 
Total net long-lived assets$749,031 $745,880 
(a) Long-lived assets consist of property and equipment, net, operating lease right-of-use assets, rental equipment and other long-term assets.
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Historical Timeline

Fiscal YearFiled
2025Feb 24, 2026Showing above
2024Feb 25, 2025
2023Mar 1, 2023
2022Mar 3, 2022
2021Mar 2, 2021
2019Feb 25, 2020
2018Feb 26, 2019
2017Feb 28, 2017
2016Mar 1, 2016

About Segments Disclosures

Segment disclosures break a company into its reportable operating units, revealing revenue, profit, and asset allocation that consolidated financial statements obscure. Under ASC 280, segments must match how the chief operating decision maker views the business, providing a window into internal management structure and resource allocation priorities.

Key signals: compare segment margins to identify which units drive profitability and which destroy value. Watch for changes in the number of reportable segments — segment aggregation or disaggregation often coincides with strategic shifts or attempts to obscure declining performance. Intersegment elimination patterns reveal internal pricing practices. The reconciliation between segment totals and consolidated figures exposes corporate overhead allocation and unallocated items. Geographic revenue concentration highlights regulatory and currency exposure. Compare segment-level capital expenditure against segment revenue to assess where management is investing for future growth versus harvesting existing assets.