Senti Biosciences Holdings, Inc. Segments Disclosure
| Years Ended December 31, | |||||||||||
| (in thousands) | 2025 | 2024 | |||||||||
| Collaboration revenue - related party | $ | 22 | $ | — | |||||||
| Operating expenses: | |||||||||||
| Research and development: | |||||||||||
| External services and supplies | 23,836 | 20,795 | |||||||||
| Personnel-related expenses, including stock-based compensation | 8,214 | 7,694 | |||||||||
| Facilities and other | 4,634 | 4,889 | |||||||||
| General and administrative: | |||||||||||
| External services and supplies | 5,463 | 7,624 | |||||||||
| Personnel-related expenses, including stock-based compensation | 11,513 | 8,379 | |||||||||
| Facilities and other | 6,452 | 7,507 | |||||||||
| Depreciation and amortization | 3,637 | 3,838 | |||||||||
| Impairment of long-lived assets | 5,052 | 313 | |||||||||
| Total operating expenses | 68,801 | 61,039 | |||||||||
| Loss from operations | (68,779) | (61,039) | |||||||||
| Interest income | 927 | 948 | |||||||||
Sublease income (1) | 6,253 | 6,608 | |||||||||
| Other income, net - related party | 160 | — | |||||||||
Other income, net (1) | 1 | 693 | |||||||||
| Net loss | $ | (61,438) | $ | (52,790) | |||||||
Historical Timeline
| Fiscal Year | Filed | |
|---|---|---|
| 2025 | Mar 27, 2026 | Showing above |
| 2024 | Mar 20, 2025 | |
About Segments Disclosures
Segment disclosures break a company into its reportable operating units, revealing revenue, profit, and asset allocation that consolidated financial statements obscure. Under ASC 280, segments must match how the chief operating decision maker views the business, providing a window into internal management structure and resource allocation priorities.
Key signals: compare segment margins to identify which units drive profitability and which destroy value. Watch for changes in the number of reportable segments — segment aggregation or disaggregation often coincides with strategic shifts or attempts to obscure declining performance. Intersegment elimination patterns reveal internal pricing practices. The reconciliation between segment totals and consolidated figures exposes corporate overhead allocation and unallocated items. Geographic revenue concentration highlights regulatory and currency exposure. Compare segment-level capital expenditure against segment revenue to assess where management is investing for future growth versus harvesting existing assets.