Theravance Biopharma, Inc.
Business
Theravance Biopharma is a biopharmaceutical company developing and commercializing respiratory medicines. The company's primary product is YUPELRI (revefenacin), an FDA-approved once-daily nebulized long-acting muscarinic antagonist for COPD maintenance treatment, co-commercialized with Viatris in the US under a profit-and-loss sharing arrangement and by Viatris outside the US under a royalty arrangement. The company also maintains economic interests in GSK's TRELEGY through milestone payments and previously held royalties on global net sales. A Phase 3 program for ampreloxetine in neurogenic orthostatic hypotension did not meet its primary endpoint, and the company is winding down that program while pursuing strategic alternatives.
Summary from 10-K filed 2026-03-23
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Total revenues | 107 | 64 | 57 | 51 | 55 | |
| Research and development | 37 | 38 | 41 | 63 | 194 | |
| Selling, general and administrative | 74 | 69 | 70 | 67 | 99 | |
| Impairment of long-lived assets (non-cash) | 0 | 5 | — | — | — | |
| Total expenses | 111 | 111 | 113 | 143 | 313 | |
| Loss from operations | −4 | −47 | −56 | −92 | −258 | |
| Net gain on realized contingent milestone and royalty assets | 75 | — | — | — | — | |
| TRELEGY milestone income | 50 | — | — | — | — | |
| Interest expense (non-cash) | −2 | −3 | −2 | — | — | |
| Interest and other income, net | 10 | 5 | 9 | 9 | 1 | |
| Income (loss) before income taxes | 129 | −45 | −49 | −93 | −265 | |
| Provision for income tax benefit (expense) | −23 | −12 | −6 | −9,000 | 200,000 | |
| Net income (loss) | 106 | −56 | −55 | 872 | −199 | |
| Net income (loss) per share - basic (in dollars per share) | 2.1 | −1.15 | −1 | 11.85 | −2.87 | |
| Net income (loss) per share - diluted (in dollars per share) | 2.06 | −1.15 | −1 | 11.85 | −2.87 | |
| Shares used to compute net income (loss) per share - basic (in shares) | 50 | 49 | 55 | 74 | 69 | |
| Shares used to compute net income (loss) per share - diluted (in shares) | 52 | 49 | 55 | 74 | 69 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2025 2025-06-30 | FY 2025 2025-03-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 168 | — | — | 38 | 40 | |
| Short-term marketable securities | 148 | — | — | 51 | 63 | |
| Receivables from collaborative arrangements | 46 | — | — | 18 | 17 | |
| Receivables from milestones and royalty assets | 50 | — | — | 50 | — | |
| Other prepaid and current assets | 8 | — | — | 4 | 12 | |
| Total current assets | 418 | — | — | 161 | 134 | |
| Long-term marketable securities | 11 | — | — | — | — | |
| Property and equipment, net | 6 | — | — | 7 | 9 | |
| Operating lease assets | 24 | — | — | 28 | 36 | |
| Future contingent milestone and royalty assets | — | 144 | 144 | 144 | 194 | |
| Restricted cash | 836,000 | — | — | 836,000 | 836,000 | |
| Other assets | 25 | — | — | 12 | 8 | |
| Total assets | 486 | — | — | 354 | 382 | |
| Accounts payable | 3 | — | — | 2 | 2 | |
| Accrued personnel-related expenses | 13 | — | — | 7 | 6 | |
| Accrued clinical and development expenses | 3 | — | — | 1 | 2 | |
| Accrued general and administrative expenses | 2 | — | — | 3 | 3 | |
| Operating lease liabilities | 11 | — | — | 11 | 4 | |
| Income tax payable | 5 | — | — | 6 | — | |
| Other accrued liabilities | 1 | — | — | 2 | 1 | |
| Total current liabilities | 38 | — | — | 32 | 25 | |
| Long-term operating lease liabilities | 32 | — | — | 39 | 45 | |
| Future royalty payment contingency | 33 | — | — | 30 | 28 | |
| Unrecognized tax benefits | 86 | — | — | 75 | — | |
| Other long-term liabilities | 313,000 | — | — | 2 | 6 | |
| Commitments and contingencies (Note 15) | — | — | — | — | — | |
| Preferred shares, $0.00001 par value per share: 230 shares authorized, no shares issued or outstanding | — | — | — | — | — | |
| Ordinary shares, $0.00001 par value per share: 200,000 shares authorized; 51,069 and 49,471 shares issued and outstanding at December 31, 2025 and December 31, 2024, respectively | 1,000 | — | — | — | — | |
| Additional paid-in capital | 1,156 | — | — | 1,141 | 1,122 | |
| Accumulated other comprehensive income | 61,000 | — | — | 7,000 | −65,000 | |
| Accumulated deficit | −860 | — | — | −966 | −909 | |
| Total shareholders' equity | 297 | — | — | 176 | 213 | |
| Total liabilities and shareholders' equity | 486 | — | — | 354 | 382 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Net income (loss) | 106 | −56 | — | — | — | |
| Depreciation and amortization | 2 | 2 | 2 | 4 | 5 | |
| Amortization and accretion on investment securities, net | −3 | −3 | −2 | −681,000 | 10,000 | |
| Future royalty payment contingency interest accretion | 2 | 3 | 2 | 974,000 | — | |
| Share-based compensation | 18 | 21 | 25 | 40 | 62 | |
| Loss on disposal of property and equipment | 35,000 | 34,000 | 1 | −8,000 | 39,000 | |
| Amortization of right-of-use assets | 4 | 4 | 4 | 4 | 4 | |
| Deferred income taxes | −12 | −8 | — | — | — | |
| Other | −89,000 | — | — | — | 10,000 | |
| Receivables from collaborative and licensing arrangements | −27 | −966,000 | −689,000 | −3 | 2 | |
| Prepaid clinical and development services | 73,000 | 2 | −526,000 | 9 | 10 | |
| Other prepaid and current assets | −3 | 7 | −4 | −704,000 | 3 | |
| Right-of-use lease assets | −32,000 | −707,000 | −314,000 | −4 | — | |
| Future contingent milestone and royalty assets | 144 | — | — | — | — | |
| Other assets | −1 | 411,000 | −1 | −4 | −972,000 | |
| Accounts payable | 326,000 | 750,000 | 6,000 | −2 | −4 | |
| Accrued personnel-related expenses, accrued clinical and development expenses, and other accrued liabilities | 4 | 1 | −7 | −14 | −37 | |
| Operating lease liabilities | −7 | 661,000 | −3 | −1 | −2 | |
| Unrecognized tax benefits | 10 | 10 | 1 | 64 | −189,000 | |
| Other long-term liabilities | 67,000 | −532,000 | 8 | −525,000 | 777,000 | |
| Net cash provided by (used in) operating activities | 239 | −12 | −27 | −187 | −208 | |
| Purchases of property and equipment | −42,000 | −332,000 | −2 | −572,000 | −3 | |
| Purchases of marketable securities | −248 | −141 | −135 | −103 | −158 | |
| Maturities of marketable securities | 143 | 140 | 31 | 158 | 286 | |
| Purchase of derivative | — | −2 | — | — | — | |
| Sale of short-term investments and marketable securities | — | 16 | 71 | 17,000 | — | |
| Net cash (used in) provided by investing activities | −105 | 12 | −33 | 1,154 | 124 | |
| Ordinary share repurchases | — | −445,000 | −197 | −129 | — | |
| Proceeds from the sale of ordinary shares | 20,000 | 99,000 | — | — | 108 | |
| Proceeds from ESPP purchases | — | 508,000 | 618,000 | 802,000 | 3 | |
| Proceeds from option exercises | 766,000 | — | — | — | 5,000 | |
| Repurchase of shares to satisfy tax withholding | −4 | −3 | −3 | −3 | −9 | |
| Net cash used in financing activities | −3 | −2 | −199 | −759 | 92 | |
| Net increase (decrease) in cash, cash equivalents, and restricted cash | 130 | −2 | −259 | 208 | 8 | |
| Cash paid for income taxes, net | 28 | 109,000 | 24,000 | 118 | −4 |
Filings
Material Events
Insiders
Institutional Holders
Frequently asked questions
What is Theravance Biopharma, Inc.'s CIK number?
Theravance Biopharma, Inc.'s SEC CIK number is 0001583107 (1583107). The CIK (Central Index Key) is the permanent identifier the SEC assigns to every EDGAR filer — unlike a ticker symbol, it never changes.
Where can I find Theravance Biopharma, Inc.'s SEC filings?
All of Theravance Biopharma, Inc.'s EDGAR filings — 10-K annual reports, 10-Q quarterly reports, 8-K material events, and insider transactions — are listed on this page, sourced live from SEC EDGAR.
When did Theravance Biopharma, Inc. last report earnings?
Theravance Biopharma, Inc. (TBPH) most recently filed an earnings 8-K with the SEC on May 7, 2026, furnishing its results under Item 2.02 (Results of Operations and Financial Condition). The earnings press release is attached to that filing (accession 0001104659-26-056733). This is Theravance Biopharma, Inc.'s most recent earnings filing of record — not a forecast of its next earnings date.
What is Theravance Biopharma, Inc.'s most recent earnings 8-K?
Theravance Biopharma, Inc.'s latest earnings 8-K (Item 2.02) was filed May 7, 2026 under accession 0001104659-26-056733. It carries the quarterly or annual earnings press release — the earliest official, SEC-filed version of the results.
View Theravance Biopharma, Inc.'s latest earnings 8-K →
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