14. Segment Reporting

Operating segments are defined as components of the entity for which separate financial information is made available and that is regularly evaluated by the chief operating decision maker (CODM) in making decisions regarding resource allocation and assessing performance. The Company's CODM is its chief executive officer and the Company manages its operations as a single segment for the purposes of assessing performance and making operating decisions. The Company is focused on the development of T cell receptor (TCR)-engineered T cell (TCR-T) therapies for the treatment of patients with cancer.

The CODM assesses the Company's performance by reviewing GAAP net loss and significant expenses by function along with the annual budget. The chief operating decision maker considers budget-to-actual variances on a quarterly basis when making decisions about the allocation of operating and capital resources.

The following table provides information about the Company's single operating segment which includes significant expenses by function along with significant non-cash expense items.

 

 

Year Ended
December 31,

 

 

2025

 

 

2024

 

Revenue:

 

 

 

 

 

Collaboration and license revenue

$

10,325

 

 

$

2,816

 

Operating expenses:

 

 

 

 

 

Research and development:

 

 

 

 

 

Laboratory supplies, research materials and studies

 

35,157

 

 

 

31,468

 

Personnel expenses

 

33,904

 

 

 

31,742

 

Facility-related and other

 

20,068

 

 

 

16,669

 

Clinical studies

 

16,847

 

 

 

19,245

 

Stock-based compensation

 

5,964

 

 

 

4,846

 

Depreciation expense

 

2,210

 

 

 

3,380

 

General and administrative:

 

 

 

 

 

Personnel expenses

 

11,415

 

 

 

10,900

 

Legal and professional fees

 

7,217

 

 

 

7,380

 

Facility-related and other

 

6,958

 

 

 

6,576

 

Stock-based compensation

 

5,742

 

 

 

4,703

 

Depreciation expense

 

656

 

 

 

728

 

Other (expense) income:

 

 

 

 

 

Interest and other income, net

 

8,816

 

 

 

12,065

 

Interest expense

 

(2,769

)

 

 

(3,653

)

Loss on extinguishment of debt

 

-

 

 

 

(1,090

)

Net Loss

$

(129,766

)

 

$

(127,499

)

Historical Timeline

Fiscal YearFiled
2025Mar 4, 2026Showing above
2024Mar 5, 2025

About Segments Disclosures

Segment disclosures break a company into its reportable operating units, revealing revenue, profit, and asset allocation that consolidated financial statements obscure. Under ASC 280, segments must match how the chief operating decision maker views the business, providing a window into internal management structure and resource allocation priorities.

Key signals: compare segment margins to identify which units drive profitability and which destroy value. Watch for changes in the number of reportable segments — segment aggregation or disaggregation often coincides with strategic shifts or attempts to obscure declining performance. Intersegment elimination patterns reveal internal pricing practices. The reconciliation between segment totals and consolidated figures exposes corporate overhead allocation and unallocated items. Geographic revenue concentration highlights regulatory and currency exposure. Compare segment-level capital expenditure against segment revenue to assess where management is investing for future growth versus harvesting existing assets.