Instil Bio, Inc.
Business
Instil Bio is a biotechnology company pursuing acquisition and in-licensing of novel therapeutic candidates for diseases with significant unmet medical need. The company previously developed proprietary folate receptor alpha co-stimulatory antigen receptor tumor infiltrating lymphocyte cell therapy for cancer and bispecific antibody candidates, with its former lead program discontinued in January 2026. Instil Bio operates through its wholly owned subsidiary Axion Bio and owns a manufacturing facility in Tarzana, California leased to AstraZeneca, serving U.S. and international markets subject to FDA and foreign regulatory oversight.
Summary from 10-K filed 2026-03-27
Financials
Consolidated Statement of Income
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| In-process research and development | 10 | 10 | 0 | — | — | |
| Research and development | 25 | 12 | 40 | — | — | |
| General and administrative | 27 | 44 | 48 | 62 | 48 | |
| Restructuring and impairment charges | 17 | 7 | 72 | 23 | 0 | |
| Total operating expenses | 79 | 74 | 159 | 226 | 156 | |
| Loss from operations | −79 | −74 | −159 | −226 | −156 | |
| Interest income | 4 | 7 | 9 | 4 | 80,000 | |
| Interest expense | −6 | −9 | −5 | — | — | |
| Other rental income | 9 | 4 | 0 | — | — | |
| Other income (expense), net | 212,000 | −3 | −575,000 | −564,000 | −1 | |
| Net loss | −71 | −74 | −156 | −223 | −157 | |
| Foreign currency translation | −342,000 | 168,000 | −433,000 | 9,000 | 246,000 | |
| Unrealized loss on available-for-sale securities, net | −13,000 | −48,000 | 578,000 | −415,000 | −50,000 | |
| Net comprehensive loss | −72 | −74 | −156 | −224 | −157 | |
| Net loss per share, basic (in dollars per share) | −10.7 | −11.39 | −24 | −34.46 | −1.48 | |
| Net loss per share, diluted (in dollars per share) | −10.7 | −11.39 | −24 | −34.46 | −1.48 | |
| Weighted-average shares used in computing net loss per share, basic (in shares) | 7 | 7 | 7 | 6 | 106 | |
| Weighted-average shares used in computing net loss per share, diluted (in shares) | 7 | 7 | 7 | 6 | 106 |
Consolidated Balance Sheet
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Cash and cash equivalents | 7 | 9 | 9 | 44 | 38 | |
| Restricted cash | 200,000 | 2 | 2 | 0 | — | |
| Marketable securities | 70 | 105 | 141 | — | — | |
| Prepaid expenses and other current assets | 3 | 9 | 9 | 8 | 10 | |
| Assets held for sale | 112 | 0 | — | — | — | |
| Total current assets | 191 | 124 | 161 | 269 | 464 | |
| Property, plant and equipment, net | 126,000 | 129 | 139 | 197 | 122 | |
| Operating lease right-of-use assets | 238,000 | 934,000 | 2 | 12 | 0 | |
| Accrued rent receivable | 8 | 4 | — | — | — | |
| Other long-term assets | 4 | 4 | 639,000 | 3 | 8 | |
| Total assets | 204 | 264 | 326 | 482 | 610 | |
| Accounts payable | 779,000 | 659,000 | 1 | 2 | 6 | |
| Accrued expenses and other current liabilities | 4 | 7 | 9 | 30 | 34 | |
| Total current liabilities | 5 | 8 | 11 | 33 | 41 | |
| Contingent consideration | 0 | 948,000 | 5 | 8 | 11 | |
| Operating lease liabilities, non-current | 0 | 1 | 3 | 5 | 0 | |
| Loan payable | 85 | 84 | 81 | 72 | 0 | |
| Other long-term liabilities | 8,000 | 83,000 | 80,000 | 332,000 | 20,000 | |
| Total liabilities | 90 | 94 | 100 | 119 | 55 | |
| Commitments and contingencies (Note 8) | — | — | — | — | — | |
| Preferred stock, par value $0.000001 per share; 10,000,000 shares authorized; zero shares issued and outstanding as of December 31, 2025, and 2024 | 0 | 0 | 0 | 0 | 0 | |
| Common stock, par value $0.000001 per share; 300,000,000 shares authorized; 6,781,976 and 6,525,887 shares issued and outstanding as of December 31, 2025, and 2024 | 0 | 0 | 0 | 0 | 0 | |
| Additional paid-in capital | 841 | 825 | 807 | 789 | 757 | |
| Accumulated other comprehensive loss | −583,000 | −228,000 | −348,000 | −493,000 | −87,000 | |
| Accumulated deficit | −726 | −655 | −581 | −425 | −202 | |
| Total stockholders equity | 114 | 169 | 226 | 364 | 555 | |
| Total liabilities and stockholders equity | 204 | 264 | 326 | 482 | 610 |
Consolidated Statement of Cash Flows
| Concept | Trend | FY 2025 2025-12-31 | FY 2024 2024-12-31 | FY 2023 2023-12-31 | FY 2022 2022-12-31 | FY 2021 2021-12-31 |
|---|---|---|---|---|---|---|
| Stock-based compensation | 9 | 17 | 18 | 30 | 26 | |
| Non-cash lease expense | 286,000 | 212,000 | 640,000 | — | — | |
| Foreign exchange remeasurement (gain) loss | −484,000 | 275,000 | −680,000 | 1 | 710,000 | |
| Impairment of property, plant and equipment | 17 | 4 | — | — | — | |
| Impairment of right-of-use assets | 0 | 827,000 | 8 | 166,000 | — | |
| Change in fair value of contingent consideration | −948,000 | −4 | −3 | −3 | 294,000 | |
| Depreciation | 534,000 | 4 | 5 | 6 | 3 | |
| Restructuring costs | −91,000 | 0 | — | — | — | |
| Accretion on invested securities | −37,000 | −4 | −7 | −1 | — | |
| Non-cash interest expense | 791,000 | 962,000 | 1 | −198,000 | 0 | |
| Non-cash loss on debt extinguishment | 0 | 415,000 | 0 | — | — | |
| Change in fair value of derivative financial instrument | 0 | 1 | 1 | −1 | 0 | |
| Loss on disposals of property and equipment | 0 | 343,000 | 377,000 | 0 | — | |
| Prepaid expenses and other current assets | 6 | −221,000 | −241,000 | −430,000 | −5 | |
| Other long-term assets | 425,000 | −4 | 2 | 354,000 | −7 | |
| Accrued rent receivable | −3 | −4 | — | — | — | |
| Accounts payable | 116,000 | −556,000 | −1 | −2 | 4 | |
| Operating lease liabilities | −1 | −1 | −1 | −335,000 | 0 | |
| Long-term liabilities | −79,000 | 77,000 | −12,000 | 2 | 0 | |
| Accrued expenses and other current liabilities | −2 | −2 | −8 | −14 | 12 | |
| Net cash used in operating activities | −37 | −56 | −82 | −180 | −122 | |
| Purchase of marketable securities | −101 | −134 | −301 | −665 | −1,108 | |
| Maturities of marketable securities | 136 | 198 | 362 | 865 | 691 | |
| Cash received from asset disposals | 432,000 | 866,000 | — | — | — | |
| Acquired in-process research and development | −10 | −10 | 0 | — | — | |
| Cash received from termination of derivative financial instrument | 0 | 605,000 | 0 | — | — | |
| Purchase of derivative financial instrument | 0 | −2 | 0 | −1 | 0 | |
| Net cash provided by investing activities | 25 | 54 | 41 | 115 | −474 | |
| Proceeds from the 2024 Loan | 0 | 86 | 0 | 70 | 0 | |
| Principal payments on Construction Loans | 0 | −83 | −587,000 | — | — | |
| Proceeds from at-the-market offering, net of $0.3 million in issuance costs | 7 | 0 | — | — | — | |
| Proceeds from exercise of stock options | 853,000 | 365,000 | 0 | 2 | 2 | |
| 2024 Loan agreement closing costs | −172,000 | −1 | 0 | — | — | |
| Net cash provided by financing activities | 7 | 2 | 8 | 72 | 393 | |
| Net (decrease) increase in cash, cash equivalents, and restricted cash | −4 | 33,000 | −33 | 6 | −203 | |
| Effect of exchange rate changes on cash, cash equivalents and restricted cash | 20,000 | −94,000 | −201,000 | −637,000 | −304,000 | |
| Cash paid for interest | 5 | 8 | 7 | 1 | 0 |
Filings
Material Events
Insiders
Institutional Holders
Frequently asked questions
What is Instil Bio, Inc.'s CIK number?
Instil Bio, Inc.'s SEC CIK number is 0001789769 (1789769). The CIK (Central Index Key) is the permanent identifier the SEC assigns to every EDGAR filer — unlike a ticker symbol, it never changes.
Where can I find Instil Bio, Inc.'s SEC filings?
All of Instil Bio, Inc.'s EDGAR filings — 10-K annual reports, 10-Q quarterly reports, 8-K material events, and insider transactions — are listed on this page, sourced live from SEC EDGAR.
When did Instil Bio, Inc. last report earnings?
Instil Bio, Inc. (TIL) most recently filed an earnings 8-K with the SEC on May 15, 2026, furnishing its results under Item 2.02 (Results of Operations and Financial Condition). The earnings press release is attached to that filing (accession 0001789769-26-000044). This is Instil Bio, Inc.'s most recent earnings filing of record — not a forecast of its next earnings date.
What is Instil Bio, Inc.'s most recent earnings 8-K?
Instil Bio, Inc.'s latest earnings 8-K (Item 2.02) was filed May 15, 2026 under accession 0001789769-26-000044. It carries the quarterly or annual earnings press release — the earliest official, SEC-filed version of the results.
View Instil Bio, Inc.'s latest earnings 8-K →
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