16.
Income Taxes

The components of loss before provision for income taxes for the periods presented were as follows (in thousands):

 

 

 

Year Ended December 31,

 

 

 

2025

 

 

2024

 

 

2023

 

Domestic

 

$

(59,472

)

 

$

(159,635

)

 

$

(225,335

)

Foreign

 

 

15

 

 

 

40

 

 

 

31

 

Total loss before provision for income taxes

 

$

(59,457

)

 

$

(159,595

)

 

$

(225,304

)

Deferred income taxes reflect the net tax effects of temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and the amounts used for income tax purposes.

The significant components of our deferred tax assets and liabilities as of the dates presented were as follows (in thousands):

 

 

 

December 31,

 

 

 

2025

 

 

2024

 

Deferred tax assets

 

 

 

 

 

 

Net operating losses

 

$

286,076

 

 

$

274,535

 

Tax credit carryforward

 

 

47,255

 

 

 

45,942

 

Nonqualifying stock options

 

 

29,335

 

 

 

31,010

 

Operating lease liabilities

 

 

19,845

 

 

 

22,912

 

Deferred revenue

 

 

3,546

 

 

 

14,996

 

Capitalized research and development

 

 

54,190

 

 

 

49,550

 

Tangible and intangible assets

 

 

4,114

 

 

 

1,963

 

Other

 

 

6,936

 

 

 

6,182

 

Total deferred tax assets

 

 

451,297

 

 

 

447,090

 

Less: Valuation allowance

 

 

(441,312

)

 

 

(435,509

)

Deferred tax assets, net of valuation allowance

 

 

9,985

 

 

 

11,581

 

Deferred tax liabilities

 

 

 

 

 

 

Tangible and intangible assets

 

 

 

 

 

 

Right-of-use assets

 

 

(9,985

)

 

 

(11,581

)

Net deferred taxes

 

$

 

 

$

 

ASC Topic 740, Income Taxes, requires that the tax benefit of net operating losses (“NOLs”), temporary differences and credit carryforwards be recorded as an asset to the extent that management assesses that realization is “more likely than not.” Realization of the future tax benefits is dependent on our ability to generate sufficient taxable income within the carryforward period. Because of our history of operating losses, management believes that recognition of the deferred tax assets arising from the above-mentioned future tax benefits is currently not likely to be realized and, accordingly, has provided a valuation allowance. The valuation allowance increased by $5.8 million and $33.1 million during the year ended December 31, 2025 and 2024, respectively.

Federal tax laws impose substantial restrictions on the utilization of NOL and credit carryforwards in the event of an ownership change, as defined in Section 382 of the Internal Revenue Code of 1986. Accordingly, our ability to utilize these carryforwards may be limited due to such ownership changes. We have completed a Section 382 analysis for changes in ownership through December 31, 2023 and continue to monitor for changes that could trigger a limitation. Based on this analysis, we do not expect to have any permanent limitations on the utilization of our federal NOLs. Under the Tax Cuts and Jobs Act of 2017 (TCJA) federal income tax law, federal NOLs incurred in 2018 and future years may be carried forward indefinitely, but the deductibility of such federal NOLs is subject to an annual limitation. NOLs generated prior to 2018 are eligible to be carried forward up to 20 years. As of December 31, 2025, we had U.S. federal NOLs of $192.5 million and U.S. federal tax credits of $53.4 million that will begin to expire in 2028. We also had $915.4 million of NOLs as of December 31, 2025 that do not expire.

In December 2023, the FASB issued ASU 2023-09. We adopted this update starting with the year ended December 31, 2025, and all prior periods presented have been conformed to the additional disclosure requirements, as applicable.

The effective tax rate of our provision for income taxes differs from the federal statutory rate for the periods presented as follows (in thousands, except percentages):

 

 

 

Year Ended December 31,

 

 

 

2025

 

 

2024

 

 

2023

 

Federal statutory tax rate

 

$

(12,489

)

 

21.0%

 

 

$

(33,515

)

 

21.0%

 

 

$

(47,314

)

 

21.0%

 

State tax, net of federal tax benefit

 

 

 

 

 

 

 

 

 

 

 

 

 

 

(26

)

 

 

 

Other foreign jurisdiction tax effect

 

 

(3

)

 

 

 

 

 

(8

)

 

 

 

 

 

(6

)

 

 

 

Effect of cross-border tax laws

 

 

3

 

 

 

 

 

 

8

 

 

 

 

 

 

6

 

 

 

 

Tax credit

 

 

(1,522

)

 

 

2.6

 

 

 

(3,821

)

 

 

2.4

 

 

 

(7,688

)

 

 

3.4

 

Nontaxable or nondeductible items

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Share-based compensation

 

 

4,286

 

 

 

(7.2

)

 

 

7,657

 

 

 

(4.8

)

 

 

6,471

 

 

 

(2.9

)

Other

 

 

309

 

 

 

(0.6

)

 

 

253

 

 

 

(0.1

)

 

 

274

 

 

 

(0.1

)

Change in unrecognized tax benefits

 

 

1,006

 

 

 

(1.7

)

 

 

1,407

 

 

 

(0.9

)

 

 

1,179

 

 

 

(0.5

)

Other

 

 

(3

)

 

 

 

 

 

 

 

 

 

 

 

(3

)

 

 

 

Change in valuation allowance

 

 

8,413

 

 

 

(14.1

)

 

 

28,019

 

 

 

(17.6

)

 

 

47,107

 

 

 

(20.9

)

Total

 

$

 

 

0.0%

 

 

$

 

 

0.0%

 

 

$

 

 

0.0%

 

 

We account for global intangible low-taxed income as period costs when incurred. No cash taxes were paid for 2025, 2024 and 2023. The majority of our operations were in the State of Washington.

We recognize, in the consolidated financial statements, the effect of a tax position when it is more likely than not, based on the technical merits, that the position will be sustained upon examination. We had unrecognized tax benefits of $11.7 million as of December 31, 2025.

A reconciliation of the beginning and ending amounts of unrecognized tax benefits for the dates presented are as follows (in thousands):

 

Balance at December 31, 2022

 

$

8,117

 

Additions in 2023

 

 

1,186

 

Balance at December 31, 2023

 

 

9,303

 

Additions in 2024

 

 

1,407

 

Balance at December 31, 2024

 

 

10,710

 

Additions in 2025

 

 

1,006

 

Balance at December 31, 2025

 

$

11,716

 

 

During the year ended December 31, 2025, 2024 and 2023, we recognized uncertain tax positions of $1.0 million, $1.4 million and $1.2 million, respectively, related to a reduction of the research and development credit deferred tax asset. Unrecognized tax benefits may change during the next twelve months for items that arise in the ordinary course of business. We do not expect a material change to our unrecognized tax benefits over the next twelve months that would have an adverse effect on our operating results.

We recognize interest and penalties accrued on any unrecognized tax benefits as a component of income tax expense. We had no accrued interest or penalties related to uncertain tax positions as of December 31, 2025 and 2024.

We file federal and certain state income tax returns, which provide varying statutes of limitations on assessments. However, because of NOL carryforwards, substantially all tax years since inception remain open to federal and state tax examination.

In July 2025, the One Big Beautiful Bill Act (OBBBA) was enacted in the U.S. The OBBBA includes significant provisions, such as the permanent extension of certain expiring provisions of the TCJA and immediate expensing of domestic research and development costs, with retroactive application beginning January 1, 2025. The enactment of the legislation did not have a material impact on our income tax rate during the year ended December 31, 2025 and is not expected to have a material impact on our income tax rate in future years.

Historical Timeline

Fiscal YearFiled
2025Feb 26, 2026Showing above
2024Mar 3, 2025
2023Feb 29, 2024
2022Feb 14, 2023
2021Feb 15, 2022
2020Feb 24, 2021
2019Feb 26, 2020

About Income Taxes Disclosures

The income tax disclosure reveals how much a company actually pays in taxes versus what the statutory rate would predict. Analysts focus on the effective tax rate (ETR) reconciliation, which breaks down every item driving the gap between the 21% federal rate and the company's reported ETR — including R&D credits, foreign rate differentials, and state taxes. Deferred tax assets (DTAs) and their valuation allowances signal management's confidence in future profitability: a rising allowance suggests the company doubts it can use accumulated tax benefits. Uncertain tax benefit (UTB) reserves quantify exposure to IRS challenges on aggressive positions.

Key signals to watch: sudden ETR drops without clear operational reasons, large increases in valuation allowances, growing UTB balances, and significant unremitted foreign earnings. Post-TCJA, pay attention to GILTI and BEAT provisions that affect multinational tax structures. Compare the cash taxes paid (from the cash flow statement) against the income tax provision to gauge earnings quality.