Property and equipment, net as of December 31, 2025 and 2024 consisted of the following (in thousands):

 

 

 

December 31,

 

 

 

2025

 

 

2024

 

Laboratory equipment

 

$

44,571

 

 

$

46,950

 

Computer equipment

 

 

5,928

 

 

 

8,337

 

Furniture and office equipment

 

 

3,890

 

 

 

4,040

 

Computer software

 

 

1,291

 

 

 

1,258

 

Construction in progress

 

 

1,103

 

 

 

2,571

 

Leasehold improvements

 

 

73,110

 

 

 

73,277

 

Total property and equipment, at cost

 

 

129,893

 

 

 

136,433

 

Less: Accumulated depreciation

 

 

(95,786

)

 

 

(87,817

)

Property and equipment, net

 

$

34,107

 

 

$

48,616

 

Historical Timeline

Fiscal YearFiled
2025Feb 26, 2026Showing above
2024Mar 3, 2025
2023Feb 29, 2024
2022Feb 14, 2023
2021Feb 15, 2022
2020Feb 24, 2021
2019Feb 26, 2020

About PP&E Disclosures

The PP&E disclosure details a company's physical asset base — land, buildings, machinery, and equipment — along with the depreciation methods and useful life assumptions that determine how these costs flow through the income statement. Capitalization policy thresholds reveal management's judgment on the boundary between expense and asset, directly affecting both reported earnings and asset values.

Key signals: changes in estimated useful lives or depreciation methods can materially shift reported earnings without any operational change. Compare capital expenditures against depreciation expense — when capex consistently trails depreciation, the asset base may be aging and underinvested. Watch for large asset impairments or write-downs that signal overvalued carrying amounts. Asset retirement obligations reveal future environmental or decommissioning costs that are often underappreciated. Compare PP&E intensity (PP&E-to-revenue) against industry peers to assess capital efficiency and competitive positioning.