Note 13 - Segment Reporting

The Company operates as a single operating segment focusing on developing innovative therapeutics targeting serious viral diseases. The Company's chief operating decision maker (CODM) is its Chief Executive Officer and President, who reviews financial information presented on a consolidated basis for purposes of making operating decisions, assessing financial performance, and allocating resources.

The measure of segment profit or loss used by the CODM to evaluate performance and allocate resources is consolidated net loss as reported in the Company's consolidated statements of operations. This measure is used by the CODM to assess its cash runway and make strategic decisions about resource allocation. The CODM does not use asset measures to evaluate segment performance or make resource allocation decisions.

Operating expenses include all costs necessary to operate the Company's business, primarily consisting of research and development and general and administrative expenses directly related to advancing the Company's programs. These expenses are reviewed by the CODM on a consolidated basis as part of evaluating the Company's overall financial performance. During the years ended December 31, 2024 and 2023, the Company generated all of its collaboration revenue from two customers, one of which is a related party (see Notes 3 - Related Party and 8 - Collaboration Agreements). For the years ended December 31, 2024 and 2023, all of the Company's revenue and long-lived assets were in the United States.

The following table presents the significant segment expenses and other segment items regularly reviewed by the Company's CODM:

 

 

Years Ended December 31,

 

 

 

2024

 

 

2023

 

Collaboration revenue ($28,520 and $4,430 from a related party)

 

$

28,520

 

 

$

7,163

 

Less:

 

 

 

 

 

 

External program expenses:

 

 

 

 

 

 

Research and discovery

 

 

8,985

 

 

 

9,741

 

ABI-6250

 

 

6,396

 

 

 

421

 

ABI-5366

 

 

6,215

 

 

 

2,869

 

ABI-1179

 

 

4,239

 

 

 

 

ABI-4334

 

 

2,646

 

 

 

1,947

 

Vebicorvir

 

 

(43

)

(1)

 

1,755

 

ABI-H3733

 

 

 

 

 

3,383

 

ABI-H2158

 

 

 

 

 

226

 

Total external program expenses

 

 

28,438

 

 

 

20,342

 

Employee and contractor-related expenses (2)

 

 

23,819

 

 

 

22,956

 

Facility and other expenses

 

 

3,676

 

 

 

5,602

 

Total research and development

 

 

55,933

 

 

 

48,900

 

General and administrative (2)

 

 

18,007

 

 

 

22,909

 

Other segment items (3)

 

 

(5,243

)

 

 

(3,418

)

Net loss

 

$

(40,177

)

 

$

(61,228

)

(1)
Reflects net amounts refundable to the Company after the final reconciliation of costs of the clinical trial conducted pursuant to the Arbutus Biopharma Agreement, which was terminated in February 2023.
(2)
Includes stock-based compensation expense, see Note 7 - Stock-Based Compensation for further details.
(3)
Other segment items include interest and other income, net, and income tax expense as reported in the Company's consolidated statements of operations and comprehensive loss.
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About Segments Disclosures

Segment disclosures break a company into its reportable operating units, revealing revenue, profit, and asset allocation that consolidated financial statements obscure. Under ASC 280, segments must match how the chief operating decision maker views the business, providing a window into internal management structure and resource allocation priorities.

Key signals: compare segment margins to identify which units drive profitability and which destroy value. Watch for changes in the number of reportable segments — segment aggregation or disaggregation often coincides with strategic shifts or attempts to obscure declining performance. Intersegment elimination patterns reveal internal pricing practices. The reconciliation between segment totals and consolidated figures exposes corporate overhead allocation and unallocated items. Geographic revenue concentration highlights regulatory and currency exposure. Compare segment-level capital expenditure against segment revenue to assess where management is investing for future growth versus harvesting existing assets.