11. Segment Reporting

The Company has one reportable segment relating to its operations. The segment derives its current revenues from research and development collaborations.

The Company’s Chief Operating Decision Maker (the CODM), its Chief Executive Officer, manages the Company’s operations on an integrated basis for the purposes of allocating resources. When evaluating the Company’s financial performance, the CODM reviews total revenues, total expenses and expenses by certain categories and makes decisions using this information.

The table below is a summary of the segment profit or loss, including significant segment expenses (in thousands):

 

 

 

Years Ended December 31,

 

 

 

2025

 

 

2024

 

Collaboration revenue

 

$

6,646

 

 

$

13,631

 

Less:

 

 

 

 

 

 

Personnel costs

 

 

44,002

 

 

 

43,684

 

Clinical programs

 

 

24,397

 

 

 

25,818

 

Research activities

 

 

6,888

 

 

 

14,692

 

Facilities costs

 

 

23,174

 

 

 

26,648

 

Other segment expenses (1)

 

 

55,889

 

 

 

113,065

 

Total operating expenses

 

 

154,350

 

 

 

223,907

 

Loss from operations

 

 

(147,704

)

 

 

(210,276

)

Other income (expense):

 

 

 

 

 

 

Interest income

 

 

11,052

 

 

 

17,288

 

Change in fair value of stock price appreciation milestones

 

 

244

 

 

 

819

 

Other income

 

 

93

 

 

 

5,907

 

Total other income

 

 

11,389

 

 

 

24,014

 

Net loss

 

$

(136,315

)

 

$

(186,262

)

 

(1) Other segment expenses include stock compensation expense, depreciation, legal fees, general & administrative expenses, and corporate expenses.

About Segments Disclosures

Segment disclosures break a company into its reportable operating units, revealing revenue, profit, and asset allocation that consolidated financial statements obscure. Under ASC 280, segments must match how the chief operating decision maker views the business, providing a window into internal management structure and resource allocation priorities.

Key signals: compare segment margins to identify which units drive profitability and which destroy value. Watch for changes in the number of reportable segments — segment aggregation or disaggregation often coincides with strategic shifts or attempts to obscure declining performance. Intersegment elimination patterns reveal internal pricing practices. The reconciliation between segment totals and consolidated figures exposes corporate overhead allocation and unallocated items. Geographic revenue concentration highlights regulatory and currency exposure. Compare segment-level capital expenditure against segment revenue to assess where management is investing for future growth versus harvesting existing assets.