Note 11. Segment Information

The Company has one operating segment and, therefore, one reportable segment, which comprises the discovery, development and commercialization of transformative therapies for cardio-metabolic diseases.

To date the Menarini License and the Menarini Supply Agreement have been the only source of revenue to the Company and all such revenues derive from Italy. The nature of the revenues are described in detail in Note 4 - Revenue.

The chief operating decision maker assesses performance and decides how to allocate resources based on consolidated net loss and loss before tax, adjusted for certain non-cash and non-operating items such as share-based compensation, change in fair value of derivatives and foreign currency gains or losses. Adjusted loss before taxes is used to monitor budget versus actuals and evaluate the operations of the Company. The measure of segment assets is reported on the balance sheet as total consolidated assets. The future prospects of the Company are highly dependent upon the results of its ongoing clinical trials and interactions with regulatory agencies. Such results and interactions are utilized together with assessment of the comparison of budget versus actuals in order to make decisions regarding the allocation of resources.

The following table presents the adjusted loss before taxes for the Company's single segment for each of the years ended December 31, 2025, 2024 and 2023:

 

 

Year ended December 31,

 

(In thousands of USD)

 

2025

 

 

2024

 

 

2023

 

Revenue

 

 

22,503

 

 

 

45,563

 

 

 

14,090

 

Interest income

 

 

27,592

 

 

 

16,881

 

 

 

11,283

 

Less:

 

 

 

 

 

 

 

 

 

Personnel expense

 

 

40,788

 

 

 

33,391

 

 

 

14,475

 

External R&D expense

 

 

85,845

 

 

 

108,012

 

 

 

109,820

 

Manufacturing expense

 

 

23,301

 

 

 

17,188

 

 

 

27,430

 

Regulatory expense

 

 

3,679

 

 

 

2,186

 

 

 

1,297

 

Commercial programs

 

 

19,296

 

 

 

12,719

 

 

 

3,025

 

General and administrative expense

 

 

15,374

 

 

 

14,438

 

 

 

16,323

 

Depreciation and amortization

 

 

478

 

 

 

299

 

 

 

115

 

Interest expense

 

 

 

 

 

 

 

 

 

Segment adjusted loss before tax

 

 

(138,666

)

 

 

(125,789

)

 

 

(147,112

)

Reconciliation to consolidated net loss

 

 

 

 

 

 

 

 

 

Share-based compensation expense

 

 

(59,425

)

 

 

(33,619

)

 

 

(24,572

)

Change in fair value - derivatives

 

 

(18,783

)

 

 

(75,593

)

 

 

(10,284

)

Foreign exchange gains/(losses)

 

 

13,055

 

 

 

(6,598

)

 

 

5,058

 

Income tax expense (benefit)

 

 

 

 

 

1

 

 

 

(27

)

Consolidated net loss for the period

 

 

(203,819

)

 

 

(241,598

)

 

 

(176,937

)

Historical Timeline

Fiscal YearFiled
2025Feb 18, 2026Showing above
2024Feb 26, 2025

About Segments Disclosures

Segment disclosures break a company into its reportable operating units, revealing revenue, profit, and asset allocation that consolidated financial statements obscure. Under ASC 280, segments must match how the chief operating decision maker views the business, providing a window into internal management structure and resource allocation priorities.

Key signals: compare segment margins to identify which units drive profitability and which destroy value. Watch for changes in the number of reportable segments — segment aggregation or disaggregation often coincides with strategic shifts or attempts to obscure declining performance. Intersegment elimination patterns reveal internal pricing practices. The reconciliation between segment totals and consolidated figures exposes corporate overhead allocation and unallocated items. Geographic revenue concentration highlights regulatory and currency exposure. Compare segment-level capital expenditure against segment revenue to assess where management is investing for future growth versus harvesting existing assets.