Property and equipment, net consisted of the following at December 31:
(In thousands)20252024
Laboratory equipment$17,567 $17,529 
Computer equipment and software7,284 6,454 
Leasehold improvements37,519 37,519 
Furniture and fixtures3,454 3,454 
Office equipment2,319 2,319 
Construction in progress2,747 897 
Total property and equipment70,890 68,172 
Less: accumulated depreciation(60,115)(56,497)
Total property and equipment, net$10,775 $11,675 

Historical Timeline

Fiscal YearFiled
2025Feb 12, 2026Showing above
2024Feb 13, 2025
2023Feb 15, 2024
2022Feb 23, 2023
2021Feb 24, 2022
2020Feb 25, 2021
2019Feb 19, 2020
2018Feb 14, 2019
2017Feb 14, 2018
2016Feb 16, 2017
2015Feb 26, 2016

About PP&E Disclosures

The PP&E disclosure details a company's physical asset base — land, buildings, machinery, and equipment — along with the depreciation methods and useful life assumptions that determine how these costs flow through the income statement. Capitalization policy thresholds reveal management's judgment on the boundary between expense and asset, directly affecting both reported earnings and asset values.

Key signals: changes in estimated useful lives or depreciation methods can materially shift reported earnings without any operational change. Compare capital expenditures against depreciation expense — when capex consistently trails depreciation, the asset base may be aging and underinvested. Watch for large asset impairments or write-downs that signal overvalued carrying amounts. Asset retirement obligations reveal future environmental or decommissioning costs that are often underappreciated. Compare PP&E intensity (PP&E-to-revenue) against industry peers to assess capital efficiency and competitive positioning.