The depreciation and amortization periods for the Company’s significant PP&E categories are as follows:
Laboratory equipment
5 to 7 years
Furniture and fixtures and office equipment
3 to 5 years
Leasehold improvementsLesser of remaining lease term or useful life
Property, equipment, and software consisted of the following as of December 31, 2025 and December 31, 2024 (in thousands):
20252024
Construction in progress$— $
Leasehold improvements12,064 12,028 
Software432 432 
Laboratory equipment14,011 15,086 
Office equipment1,486 1,486 
Furniture and fixtures2,124 2,124 
Total property, equipment and software30,117 31,165 
Less accumulated depreciation and amortization28,692 28,076 
Property, equipment and software - net$1,425 $3,089 

Historical Timeline

Fiscal YearFiled
2025Mar 12, 2026Showing above
2024Mar 26, 2025
2023Mar 27, 2024
2022Mar 9, 2023
2021Mar 15, 2022
2020Mar 18, 2021

About PP&E Disclosures

The PP&E disclosure details a company's physical asset base — land, buildings, machinery, and equipment — along with the depreciation methods and useful life assumptions that determine how these costs flow through the income statement. Capitalization policy thresholds reveal management's judgment on the boundary between expense and asset, directly affecting both reported earnings and asset values.

Key signals: changes in estimated useful lives or depreciation methods can materially shift reported earnings without any operational change. Compare capital expenditures against depreciation expense — when capex consistently trails depreciation, the asset base may be aging and underinvested. Watch for large asset impairments or write-downs that signal overvalued carrying amounts. Asset retirement obligations reveal future environmental or decommissioning costs that are often underappreciated. Compare PP&E intensity (PP&E-to-revenue) against industry peers to assess capital efficiency and competitive positioning.