Property and equipment consisted of the following amounts (in thousands):

As of December 31, 

As of December 31,

  ​ ​ ​

2025

  ​ ​ ​

2024

Leasehold improvements

$

9,646

$

9,646

Laboratory equipment

4,070

3,735

Computers and software

296

296

Furniture and fixtures

511

511

Construction in process

77

Property and equipment, at cost

14,600

14,188

Less: accumulated depreciation

(6,769)

(4,685)

Property and equipment, net

$

7,831

$

9,503

About PP&E Disclosures

The PP&E disclosure details a company's physical asset base — land, buildings, machinery, and equipment — along with the depreciation methods and useful life assumptions that determine how these costs flow through the income statement. Capitalization policy thresholds reveal management's judgment on the boundary between expense and asset, directly affecting both reported earnings and asset values.

Key signals: changes in estimated useful lives or depreciation methods can materially shift reported earnings without any operational change. Compare capital expenditures against depreciation expense — when capex consistently trails depreciation, the asset base may be aging and underinvested. Watch for large asset impairments or write-downs that signal overvalued carrying amounts. Asset retirement obligations reveal future environmental or decommissioning costs that are often underappreciated. Compare PP&E intensity (PP&E-to-revenue) against industry peers to assess capital efficiency and competitive positioning.