Property and equipment, net, as of December 31, 2025 and 2024 was comprised as follows (in thousands):

 

 

Estimated Useful Life (in Years)

 

December 31,

 

 

 

 

 

2025

 

 

2024

 

Laboratory equipment

 

5

 

$

8,312

 

 

$

11,331

 

Furniture and office equipment

 

4

 

 

651

 

 

 

1,075

 

Computer equipment

 

3

 

 

89

 

 

 

87

 

Leasehold improvements

 

Shorter of useful life or remaining lease term

 

 

9,681

 

 

 

22,438

 

Construction in progress

 

 

 

 

 

 

 

107

 

Total property and equipment, gross

 

 

 

 

18,733

 

 

 

35,038

 

Less: accumulated depreciation

 

 

 

 

(10,569

)

 

 

(7,328

)

Total property and equipment, net

 

 

 

$

8,164

 

 

$

27,710

 

Historical Timeline

Fiscal YearFiled
2025Mar 12, 2026Showing above
2024Mar 18, 2025
2023Mar 26, 2024
2022Mar 10, 2023
2021Mar 15, 2022
2020Mar 29, 2021
2019Mar 26, 2020

About PP&E Disclosures

The PP&E disclosure details a company's physical asset base — land, buildings, machinery, and equipment — along with the depreciation methods and useful life assumptions that determine how these costs flow through the income statement. Capitalization policy thresholds reveal management's judgment on the boundary between expense and asset, directly affecting both reported earnings and asset values.

Key signals: changes in estimated useful lives or depreciation methods can materially shift reported earnings without any operational change. Compare capital expenditures against depreciation expense — when capex consistently trails depreciation, the asset base may be aging and underinvested. Watch for large asset impairments or write-downs that signal overvalued carrying amounts. Asset retirement obligations reveal future environmental or decommissioning costs that are often underappreciated. Compare PP&E intensity (PP&E-to-revenue) against industry peers to assess capital efficiency and competitive positioning.