13. Segment Reporting

 

The Company operates as a single reporting segment, focused on the research and development of cell therapies for patients with autoimmune diseases. The Company's measure of segment profit or loss is net loss. The Chief Executive Officer, as the CODM, manages and allocates resources to the operations of the Company on a total company basis. The Company monitors its cash, cash equivalents, and investments as reported on the Company's Balance Sheets to determine funding for its research and development.

 

As the Company is not yet generating revenue, the CODM evaluates its performance based on progress in pre-clinical and clinical research objectives. Along with the Company’s Statement of Operations and Comprehensive Loss, the CODM regularly reviews budgeted and forecasted expenses to assess liquidity requirements and allocate cash accordingly.

 

The following table is representative of the significant expense categories regularly provided to the CODM when managing the Company's single reporting segment.

 

A reconciliation to the net loss for the years ended December 31, 2024 and 2023 is included at the bottom of the table below.

 

 

 

December 31,

 

 

 

2024

 

 

2023

 

Segment expenses:

 

 

 

 

 

 

Personnel related expenses, excluding share-based compensation

 

$

41,129

 

 

$

42,329

 

Facilities expenses

 

 

19,403

 

 

 

16,392

 

Direct external development program expenses

 

 

21,431

 

 

 

29,517

 

Other segment expenses (1)

 

 

20,348

 

 

 

16,244

 

Total segment expenses:

 

 

102,311

 

 

 

104,482

 

Segment loss

 

 

(102,311

)

 

 

(104,482

)

 

 

 

 

 

 

 

Reconciling items:

 

 

 

 

 

 

Depreciation and amortization

 

 

(9,152

)

 

 

(5,869

)

Share-based compensation

 

 

(16,731

)

 

 

(17,199

)

Impairment of ROU asset

 

 

 

 

 

(4,100

)

Interest income

 

 

19,317

 

 

 

14,107

 

Other income, net

 

 

87

 

 

 

42

 

Net loss

 

$

(108,790

)

 

$

(117,501

)

 

(1) Other segment items include consultants and contractor, lab supplies, and general business expenses.
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About Segments Disclosures

Segment disclosures break a company into its reportable operating units, revealing revenue, profit, and asset allocation that consolidated financial statements obscure. Under ASC 280, segments must match how the chief operating decision maker views the business, providing a window into internal management structure and resource allocation priorities.

Key signals: compare segment margins to identify which units drive profitability and which destroy value. Watch for changes in the number of reportable segments — segment aggregation or disaggregation often coincides with strategic shifts or attempts to obscure declining performance. Intersegment elimination patterns reveal internal pricing practices. The reconciliation between segment totals and consolidated figures exposes corporate overhead allocation and unallocated items. Geographic revenue concentration highlights regulatory and currency exposure. Compare segment-level capital expenditure against segment revenue to assess where management is investing for future growth versus harvesting existing assets.