4. Fair Value Measurements

The following tables present the Company’s fair value hierarchy for its assets and liabilities, which are measured at fair value on a recurring basis (in thousands):

 

 

Fair Value Measurements at December 31, 2025

 

 

 

Level 1

 

 

Level 2

 

 

Level 3

 

 

Total

 

Assets:

 

 

 

 

 

 

 

 

 

 

 

 

Cash equivalents

 

$

251,567

 

 

$

 

 

$

 

 

$

251,567

 

Marketable securities:

 

 

 

 

 

 

 

 

 

 

 

 

Commercial paper

 

 

 

 

 

107,884

 

 

 

 

 

 

107,884

 

Corporate bonds

 

 

 

 

 

774,506

 

 

 

 

 

 

774,506

 

Government and agency securities

 

 

 

 

 

207,990

 

 

 

 

 

 

207,990

 

U.S. treasury bills

 

 

 

 

 

19,827

 

 

 

 

 

 

19,827

 

 

 

$

251,567

 

 

$

1,110,207

 

 

$

 

 

$

1,361,774

 

Liabilities:

 

 

 

 

 

 

 

 

 

 

 

 

Related party revenue share liability

 

$

 

 

$

 

 

$

73,160

 

 

$

73,160

 

 

 

 

Fair Value Measurements at December 31, 2024

 

 

 

Level 1

 

 

Level 2

 

 

Level 3

 

 

Total

 

Assets:

 

 

 

 

 

 

 

 

 

 

 

 

Cash equivalents

 

$

135,902

 

 

$

 

 

$

 

 

$

135,902

 

Marketable securities:

 

 

 

 

 

 

 

 

 

 

 

 

Commercial paper

 

 

 

 

 

251,309

 

 

 

 

 

 

251,309

 

Corporate bonds

 

 

 

 

 

468,617

 

 

 

 

 

 

468,617

 

Government and agency securities

 

 

 

 

 

162,886

 

 

 

 

 

 

162,886

 

U.S. treasury bills

 

 

 

 

 

89,799

 

 

 

 

 

 

89,799

 

 

 

$

135,902

 

 

$

972,611

 

 

$

 

 

$

1,108,513

 

Liabilities:

 

 

 

 

 

 

 

 

 

 

 

 

Related party revenue share liability

 

$

 

 

$

 

 

$

17,940

 

 

$

17,940

 

Cash equivalents were valued by the Company based on quoted market prices for identical securities, which represent a Level 1 measurement within the fair value hierarchy. Commercial paper, corporate bonds, government and agency securities, and U.S. treasury bills were valued by the Company using quoted prices in active markets for similar securities, which represent a Level 2 measurement within the fair value hierarchy. During the periods presented, there were no transfers in or out of Level 3. The carrying values of the Company’s accounts payable and accrued expenses and other current liabilities approximate their fair values due to the short-term nature of these liabilities.

The following table sets forth the changes in estimated fair value of the Company’s related party revenue share liability for the year ended December 31, 2025, which represents a Level 3 measurement within the fair value hierarchy (in thousands):

Estimated fair value as of December 31, 2024

 

$

17,940

 

Change in fair value

 

 

55,220

 

Estimated fair value as of December 31, 2025

 

$

73,160

 

The fair value of the related party revenue share liability was estimated using a discounted cash flow model to calculate the estimated payments that could become due following commercialization. Assumptions in the model include but are not limited to the following: probability and timing of product approval, future product revenues and discount rate. Changes in fair value each reporting period are recognized as a component of other income (expense) in the consolidated statements of operations and comprehensive loss. See Note 10 for additional information regarding the revenue sharing agreement with Deerfield.

Historical Timeline

Fiscal YearFiled
2025Feb 26, 2026Showing above
2024Feb 27, 2025
2023Feb 27, 2024
2022Mar 16, 2023
2021Mar 29, 2022

About Fair Value Disclosures

Fair value disclosures classify all assets and liabilities measured at fair value into a three-level hierarchy: Level 1 (quoted market prices), Level 2 (observable inputs like yield curves), and Level 3 (unobservable inputs requiring management estimates). The proportion of Level 3 assets directly reflects how much of the balance sheet depends on internal models rather than market evidence.

Key signals: a growing Level 3 balance relative to total fair-value assets increases valuation uncertainty and earnings volatility risk. Watch for transfers between levels — assets moving from Level 2 to Level 3 often signal deteriorating market liquidity. Unrealized gains and losses on Level 3 positions flow through earnings or other comprehensive income, so large swings deserve scrutiny. For financial institutions, examine the sensitivity disclosures that show how Level 3 valuations change under alternative assumptions. Compare the fair value of debt against its carrying amount to gauge hidden leverage.