Estimated useful lives of the major classes of property and equipment are as follows:
Estimated Useful Lives
Leasehold improvements8 years
Lab equipment
3 to 5 years
Computer equipment
3 to 5 years
Computer software3 years
Furniture and fixtures
3 to 5 years
Property and equipment, net, consisted of the following components:
December 31,
(In thousands)20252024
Laboratory equipment and machinery $47,742 $47,273 
Leasehold improvements33,837 33,770 
Computer equipment19,477 18,882 
Software7,197 7,280 
Furniture and fixtures2,954 2,972 
Construction in progress5,409 2,276 
Total116,616 112,453 
Less: Accumulated depreciation (92,470)(81,948)
Property and equipment, net $24,146 $30,505 

Historical Timeline

Fiscal YearFiled
2025Feb 25, 2026Showing above
2024Mar 17, 2025
2023Feb 28, 2024
2022Feb 28, 2023
2021Feb 28, 2022
2020Feb 26, 2021

About PP&E Disclosures

The PP&E disclosure details a company's physical asset base — land, buildings, machinery, and equipment — along with the depreciation methods and useful life assumptions that determine how these costs flow through the income statement. Capitalization policy thresholds reveal management's judgment on the boundary between expense and asset, directly affecting both reported earnings and asset values.

Key signals: changes in estimated useful lives or depreciation methods can materially shift reported earnings without any operational change. Compare capital expenditures against depreciation expense — when capex consistently trails depreciation, the asset base may be aging and underinvested. Watch for large asset impairments or write-downs that signal overvalued carrying amounts. Asset retirement obligations reveal future environmental or decommissioning costs that are often underappreciated. Compare PP&E intensity (PP&E-to-revenue) against industry peers to assess capital efficiency and competitive positioning.