Property and equipment, net consisted of the following (in thousands):
December 31,
20242023
Laboratory equipment10,988 10,410 
Leasehold improvements2,118 1,663 
Furniture and Fixture1,775 — 
Computer equipment and software1,105 124 
Construction-in-progress346 52 
Total property and equipment, gross16,332 12,249 
Less: Accumulated depreciation(10,807)(8,682)
Total property and equipment, net5,525 3,567 

About PP&E Disclosures

The PP&E disclosure details a company's physical asset base — land, buildings, machinery, and equipment — along with the depreciation methods and useful life assumptions that determine how these costs flow through the income statement. Capitalization policy thresholds reveal management's judgment on the boundary between expense and asset, directly affecting both reported earnings and asset values.

Key signals: changes in estimated useful lives or depreciation methods can materially shift reported earnings without any operational change. Compare capital expenditures against depreciation expense — when capex consistently trails depreciation, the asset base may be aging and underinvested. Watch for large asset impairments or write-downs that signal overvalued carrying amounts. Asset retirement obligations reveal future environmental or decommissioning costs that are often underappreciated. Compare PP&E intensity (PP&E-to-revenue) against industry peers to assess capital efficiency and competitive positioning.