Prime Medicine, Inc. PP&E Disclosure
Asset Class | Estimated Useful Life | |||||||
| Laboratory equipment | 5 years | |||||||
| Furniture and fixtures | 5 years | |||||||
Computer hardware and software | 3 years | |||||||
| Leasehold improvements | Shorter of remaining lease term or useful life | |||||||
| December 31, | ||||||||||||||
| (in thousands) | 2025 | 2024 | ||||||||||||
| Property and equipment: | ||||||||||||||
| Laboratory equipment | $ | 29,744 | $ | 27,343 | ||||||||||
| Leasehold improvement | 7,911 | 5,136 | ||||||||||||
| Furniture and fixture | 1,864 | 1,075 | ||||||||||||
| Computer hardware and software | 1,122 | 869 | ||||||||||||
| Construction in progress | 365 | 3,578 | ||||||||||||
| Total property and equipment | 41,006 | 38,001 | ||||||||||||
| Less: Accumulated depreciation | (20,434) | (13,597) | ||||||||||||
| Total property and equipment, net | $ | 20,572 | $ | 24,404 | ||||||||||
| Year ended December 31, | ||||||||||||||
| (in thousands) | 2025 | 2024 | ||||||||||||
| Depreciation expense | $ | 7,321 | $ | 6,128 | ||||||||||
Historical Timeline
| Fiscal Year | Filed | |
|---|---|---|
| 2025 | Mar 3, 2026 | Showing above |
| 2024 | Feb 28, 2025 | |
| 2023 | Mar 1, 2024 | |
| 2022 | Mar 9, 2023 | |
About PP&E Disclosures
The PP&E disclosure details a company's physical asset base — land, buildings, machinery, and equipment — along with the depreciation methods and useful life assumptions that determine how these costs flow through the income statement. Capitalization policy thresholds reveal management's judgment on the boundary between expense and asset, directly affecting both reported earnings and asset values.
Key signals: changes in estimated useful lives or depreciation methods can materially shift reported earnings without any operational change. Compare capital expenditures against depreciation expense — when capex consistently trails depreciation, the asset base may be aging and underinvested. Watch for large asset impairments or write-downs that signal overvalued carrying amounts. Asset retirement obligations reveal future environmental or decommissioning costs that are often underappreciated. Compare PP&E intensity (PP&E-to-revenue) against industry peers to assess capital efficiency and competitive positioning.