Property and equipment, net consist of the following (in thousands):
December 31,
20242023
Laboratory equipment$21,391 $34,630 
Leasehold improvements24,923 29,809 
Furniture and fixtures3,546 4,610 
Manufacturing equipment7,845 7,784 
Construction in progress— 1,087 
57,705 77,920 
Less: accumulated depreciation and amortization(39,818)(51,046)
Property and equipment, net$17,887 $26,874 

Historical Timeline

Fiscal YearFiled
2024Mar 17, 2025Showing above
2023Mar 13, 2024
2018Mar 1, 2019
2017Mar 1, 2018
2016Feb 28, 2017
2015Feb 18, 2016

About PP&E Disclosures

The PP&E disclosure details a company's physical asset base — land, buildings, machinery, and equipment — along with the depreciation methods and useful life assumptions that determine how these costs flow through the income statement. Capitalization policy thresholds reveal management's judgment on the boundary between expense and asset, directly affecting both reported earnings and asset values.

Key signals: changes in estimated useful lives or depreciation methods can materially shift reported earnings without any operational change. Compare capital expenditures against depreciation expense — when capex consistently trails depreciation, the asset base may be aging and underinvested. Watch for large asset impairments or write-downs that signal overvalued carrying amounts. Asset retirement obligations reveal future environmental or decommissioning costs that are often underappreciated. Compare PP&E intensity (PP&E-to-revenue) against industry peers to assess capital efficiency and competitive positioning.