Property and equipment, net, consists of the following:

 

 

December 31,

 

 

 

2025

 

 

2024

 

 

 

(in thousands)

 

Computer equipment and software

 

$

1,475

 

 

$

1,623

 

Furniture and office equipment

 

 

110

 

 

 

244

 

Laboratory equipment

 

 

23,921

 

 

 

40,251

 

Leasehold improvements

 

 

12,343

 

 

 

24,205

 

Construction in progress

 

 

151

 

 

 

497

 

Total

 

 

38,000

 

 

 

66,820

 

Less accumulated depreciation and amortization

 

 

(27,352

)

 

 

(48,630

)

Total property and equipment, net

 

$

10,648

 

 

$

18,190

 

Historical Timeline

Fiscal YearFiled
2025Mar 23, 2026Showing above
2024Mar 13, 2025
2023Mar 25, 2024
2022Mar 30, 2023
2021Feb 28, 2022
2020Mar 18, 2021
2019Mar 16, 2020
2018Apr 1, 2019

About PP&E Disclosures

The PP&E disclosure details a company's physical asset base — land, buildings, machinery, and equipment — along with the depreciation methods and useful life assumptions that determine how these costs flow through the income statement. Capitalization policy thresholds reveal management's judgment on the boundary between expense and asset, directly affecting both reported earnings and asset values.

Key signals: changes in estimated useful lives or depreciation methods can materially shift reported earnings without any operational change. Compare capital expenditures against depreciation expense — when capex consistently trails depreciation, the asset base may be aging and underinvested. Watch for large asset impairments or write-downs that signal overvalued carrying amounts. Asset retirement obligations reveal future environmental or decommissioning costs that are often underappreciated. Compare PP&E intensity (PP&E-to-revenue) against industry peers to assess capital efficiency and competitive positioning.