Goodwill and Other Intangible Assets
Intangible Assets
Other intangible assets, net” consisted of the following:
As of December 31, 2025
As of December 31, 2024
Estimated
Useful lives
Gross
Carrying
Amount
Accumulated
Amortization
Net
Carrying
Amount
Gross
Carrying
Amount
Accumulated
Amortization
Net
Carrying
Amount
(in millions, except useful lives)
In-process research and
development
Indefinite
$224.6
$
$224.6
$603.6
$
$603.6
Finite-lived intangible assets -
marketed products
10 to 12 years
238.0
(42.1)
195.9
238.0
(21.9)
216.1
Finite-lived intangible assets -
assembled workforce
3 years
7.7
(4.0)
3.7
7.7
(1.5)
$6.2
Total other intangible assets,
net
$470.3
$(46.1)
$424.2
$849.3
$(23.4)
$825.9
In March 2025, based on results from a Phase 1/2 clinical trial evaluating our VX-264 clinical program in patients with
T1D, we concluded that VX-264 will not be advancing further in clinical development. Based on this event, we performed an
interim impairment test on the fair value of our VX-264 indefinite-lived in-process research and development asset that we
acquired from Semma Therapeutics, Inc. in 2019. As a result, using the multi period earnings method of the income
approach, we recorded a full intangible asset impairment charge of $379.0 million in the first quarter of 2025. As of
December 31, 2025, our remaining indefinite-lived in-process research and development assets were associated with our T1D
program.
In 2023, we recorded a total of $238.0 million of finite-lived intangible assets following the regulatory approval of
CASGEVY in several markets, which we are amortizing on a straight-line basis over the longer of the last underlying patents
to expire or the period that we have exclusive rights to market CASGEVY. We recorded intangible asset amortization
expense of $20.2 million, $20.2 million and $1.7 million to “Cost of sales” related to these assets in in 2025, 2024 and 2023,
respectively.
As of December 31, 2025, the estimated future amortization of our finite-lived intangible assets was as follows:
Year
Estimated Amortization Expense
(in millions)
2026
$22.7
2027
$21.3
2028
$20.2
2029
$20.2
2030
$20.2
Goodwill
As of December 31, 2025 and 2024, we had goodwill of $1.1 billion on our consolidated balance sheets.
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Historical Timeline

Fiscal YearFiled
2025Feb 13, 2026Showing above
2024Feb 13, 2025
2023Feb 15, 2024
2022Feb 10, 2023
2021Feb 9, 2022
2020Feb 11, 2021
2019Feb 13, 2020
2018Feb 13, 2019
2017Feb 15, 2018
2016Feb 23, 2017
2015Feb 16, 2016

About Goodwill & Intangibles Disclosures

Goodwill and intangible asset disclosures reveal the premium paid in acquisitions and how management assesses whether that premium retains its value. Since goodwill is no longer amortized under US GAAP, the annual impairment test is the only mechanism that adjusts carrying values downward — making the assumptions behind that test critically important for investors.

Key signals: a history of goodwill impairments suggests management consistently overpays for acquisitions. Watch the gap between reporting unit fair value and carrying amount — when fair value exceeds carrying amount by less than 10-20%, a small decline in business performance could trigger a write-down. For finite-lived intangibles, examine useful life assumptions across customer relationships, technology, and trade names; aggressive estimates inflate near-term earnings. Compare total intangibles-to-total-assets ratios against peers to assess acquisition dependency. Rising goodwill as a percentage of equity can signal balance sheet fragility.