Property and Equipment, Net
December 31,
20242023
(in thousands)
Leasehold improvements$108,127 $108,621 
Laboratory equipment31,595 33,157 
Computer equipment and purchased software4,658 4,663 
Furniture and fixtures4,214 4,121 
Total148,594 150,562 
Less: accumulated depreciation(62,538)(51,084)
Total property and equipment, net$86,056 $99,478 

Historical Timeline

Fiscal YearFiled
2024Mar 13, 2025Showing above
2020Feb 25, 2021
2019Feb 27, 2020
2018Mar 8, 2019

About PP&E Disclosures

The PP&E disclosure details a company's physical asset base — land, buildings, machinery, and equipment — along with the depreciation methods and useful life assumptions that determine how these costs flow through the income statement. Capitalization policy thresholds reveal management's judgment on the boundary between expense and asset, directly affecting both reported earnings and asset values.

Key signals: changes in estimated useful lives or depreciation methods can materially shift reported earnings without any operational change. Compare capital expenditures against depreciation expense — when capex consistently trails depreciation, the asset base may be aging and underinvested. Watch for large asset impairments or write-downs that signal overvalued carrying amounts. Asset retirement obligations reveal future environmental or decommissioning costs that are often underappreciated. Compare PP&E intensity (PP&E-to-revenue) against industry peers to assess capital efficiency and competitive positioning.