The estimated useful lives of property, plant, and equipment are as follows:
Building and improvements
10–50 years
Laboratory and other equipment
3–10 years
Furniture and fixtures
5 years
Property, plant, and equipment, net consists of the following:
As of December 31,
(In millions)20252024
Building and improvements$3,105.9 $2,573.2 
Leasehold improvements174.4 154.5 
Laboratory equipment1,543.7 1,494.5 
Computer equipment and software522.0 450.8 
Furniture, office equipment, and other
219.7 203.8 
Land278.8 288.2 
Construction in progress1,890.2 1,721.6 
7,734.7 6,886.6 
Accumulated depreciation and amortization
(2,614.3)(2,286.9)
$5,120.4 $4,599.7 

Historical Timeline

Fiscal YearFiled
2025Feb 4, 2026Showing above
2024Feb 5, 2025
2023Feb 5, 2024
2022Feb 6, 2023
2021Feb 7, 2022
2020Feb 8, 2021
2019Feb 7, 2020
2018Feb 7, 2019
2017Feb 8, 2018
2016Feb 9, 2017
2015Feb 11, 2016

About PP&E Disclosures

The PP&E disclosure details a company's physical asset base — land, buildings, machinery, and equipment — along with the depreciation methods and useful life assumptions that determine how these costs flow through the income statement. Capitalization policy thresholds reveal management's judgment on the boundary between expense and asset, directly affecting both reported earnings and asset values.

Key signals: changes in estimated useful lives or depreciation methods can materially shift reported earnings without any operational change. Compare capital expenditures against depreciation expense — when capex consistently trails depreciation, the asset base may be aging and underinvested. Watch for large asset impairments or write-downs that signal overvalued carrying amounts. Asset retirement obligations reveal future environmental or decommissioning costs that are often underappreciated. Compare PP&E intensity (PP&E-to-revenue) against industry peers to assess capital efficiency and competitive positioning.