Property and equipment consists of the following (in thousands):
 December 31,
 20242023
Laboratory equipment$7,295 $6,280 
Computer equipment and software415 702 
Leasehold improvements3,427 61 
Furniture and fixtures268 452 
Office equipment169 196 
Construction in process695 150 
Total property and equipment12,269 7,841 
Less accumulated depreciation(2,357)(5,728)
Property and equipment, net$9,912 $2,113 

About PP&E Disclosures

The PP&E disclosure details a company's physical asset base — land, buildings, machinery, and equipment — along with the depreciation methods and useful life assumptions that determine how these costs flow through the income statement. Capitalization policy thresholds reveal management's judgment on the boundary between expense and asset, directly affecting both reported earnings and asset values.

Key signals: changes in estimated useful lives or depreciation methods can materially shift reported earnings without any operational change. Compare capital expenditures against depreciation expense — when capex consistently trails depreciation, the asset base may be aging and underinvested. Watch for large asset impairments or write-downs that signal overvalued carrying amounts. Asset retirement obligations reveal future environmental or decommissioning costs that are often underappreciated. Compare PP&E intensity (PP&E-to-revenue) against industry peers to assess capital efficiency and competitive positioning.