Property and equipment, net consists of the following (in thousands):

 

 

 

December 31,

 

 

 

2024

 

 

2023

 

Laboratory equipment

 

$

28,723

 

 

$

28,563

 

Computer equipment and software

 

 

1,984

 

 

 

868

 

Furniture and fixtures

 

 

681

 

 

 

672

 

Leasehold improvements

 

 

3,577

 

 

 

3,520

 

Construction-in-progress

 

 

424

 

 

 

1,109

 

Property and equipment

 

 

35,389

 

 

 

34,732

 

Less: accumulated depreciation and amortization

 

 

(16,814

)

 

 

(12,539

)

Total property and equipment, net

 

$

18,575

 

 

$

22,193

 

About PP&E Disclosures

The PP&E disclosure details a company's physical asset base — land, buildings, machinery, and equipment — along with the depreciation methods and useful life assumptions that determine how these costs flow through the income statement. Capitalization policy thresholds reveal management's judgment on the boundary between expense and asset, directly affecting both reported earnings and asset values.

Key signals: changes in estimated useful lives or depreciation methods can materially shift reported earnings without any operational change. Compare capital expenditures against depreciation expense — when capex consistently trails depreciation, the asset base may be aging and underinvested. Watch for large asset impairments or write-downs that signal overvalued carrying amounts. Asset retirement obligations reveal future environmental or decommissioning costs that are often underappreciated. Compare PP&E intensity (PP&E-to-revenue) against industry peers to assess capital efficiency and competitive positioning.