Property and equipment, net consist of the following (in thousands):

 

 

 

December 31,

 

 

 

2024

 

 

2023

 

Laboratory equipment

 

$

4,233

 

 

$

4,023

 

Leasehold improvements

 

 

1,655

 

 

 

1,588

 

Office equipment

 

 

165

 

 

 

157

 

Software

 

 

104

 

 

 

104

 

Total

 

 

6,157

 

 

 

5,872

 

Less accumulated depreciation and amortization

 

 

(4,640

)

 

 

(3,671

)

Total

 

 

1,517

 

 

 

2,201

 

Construction-in-progress

 

 

31

 

 

 

3,904

 

Total property and equipment, net

 

$

1,548

 

 

$

6,105

 

 

As of December 31, 2024, the Company recognized an impairment loss of $3.7 million related to construction-in-progress property and equipment (Note 2).

About PP&E Disclosures

The PP&E disclosure details a company's physical asset base — land, buildings, machinery, and equipment — along with the depreciation methods and useful life assumptions that determine how these costs flow through the income statement. Capitalization policy thresholds reveal management's judgment on the boundary between expense and asset, directly affecting both reported earnings and asset values.

Key signals: changes in estimated useful lives or depreciation methods can materially shift reported earnings without any operational change. Compare capital expenditures against depreciation expense — when capex consistently trails depreciation, the asset base may be aging and underinvested. Watch for large asset impairments or write-downs that signal overvalued carrying amounts. Asset retirement obligations reveal future environmental or decommissioning costs that are often underappreciated. Compare PP&E intensity (PP&E-to-revenue) against industry peers to assess capital efficiency and competitive positioning.