Property and equipment, net consists of the following (in thousands):
December 31,
20252024
Office equipment$24,411 $23,710 
Laboratory equipment258,003 229,797 
Computer equipment152,156 156,859 
Land11,273 15,395 
Building and leasehold improvements610,027 597,342 
Operating lease right-of-use assets19,596 22,230 
Construction in progress30,485 46,062 
1,105,951 1,091,395 
Less accumulated depreciation and amortization(375,066)(327,984)
Property and equipment, net$730,885 $763,411 

Historical Timeline

Fiscal YearFiled
2025Feb 10, 2026Showing above
2024Feb 10, 2025
2023Feb 13, 2024
2022Feb 7, 2023
2021Feb 8, 2022
2020Feb 9, 2021
2019Feb 13, 2020
2018Feb 14, 2019
2017Feb 15, 2018
2016Feb 14, 2017
2015Feb 12, 2016

About PP&E Disclosures

The PP&E disclosure details a company's physical asset base — land, buildings, machinery, and equipment — along with the depreciation methods and useful life assumptions that determine how these costs flow through the income statement. Capitalization policy thresholds reveal management's judgment on the boundary between expense and asset, directly affecting both reported earnings and asset values.

Key signals: changes in estimated useful lives or depreciation methods can materially shift reported earnings without any operational change. Compare capital expenditures against depreciation expense — when capex consistently trails depreciation, the asset base may be aging and underinvested. Watch for large asset impairments or write-downs that signal overvalued carrying amounts. Asset retirement obligations reveal future environmental or decommissioning costs that are often underappreciated. Compare PP&E intensity (PP&E-to-revenue) against industry peers to assess capital efficiency and competitive positioning.